Oncogene Protein gp140(v-fms)
"Oncogene Protein gp140(v-fms)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).
| Descriptor ID |
D016281
|
| MeSH Number(s) |
D12.776.624.664.520.750.650 D12.776.964.700.750.650 D12.776.964.775.750.650
|
| Concept/Terms |
Oncogene Protein gp140(v-fms)- Oncogene Protein gp140(v-fms)
- fms Oncogene Protein gp140
- v-fms Protein
- v fms Protein
- gp140(v-fms)
- fms Oncogene Product gp140
- gp140 v-fms
- gp140 v fms
- v-fms, gp140
|
Below are MeSH descriptors whose meaning is more general than "Oncogene Protein gp140(v-fms)".
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Below are the most recent publications written about "Oncogene Protein gp140(v-fms)" by people in Profiles.
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Excess early signaling activity inhibits cellular chemotaxis toward PDGF-BB. Oncogene. 1994 May; 9(5):1429-35.