Mi-2 Nucleosome Remodeling and Deacetylase Complex
"Mi-2 Nucleosome Remodeling and Deacetylase Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A enzyme complex involved in the remodeling of NUCLEOSOMES. The complex is comprised of at least seven subunits and includes both histone deacetylase and ATPase activities.
| Descriptor ID |
D056245
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| MeSH Number(s) |
D08.811.277.040.025.176 D08.811.277.087.520.500 D08.811.600.620
|
| Concept/Terms |
Mi-2 Nucleosome Remodeling and Deacetylase Complex- Mi-2 Nucleosome Remodeling and Deacetylase Complex
- Mi 2 Nucleosome Remodeling and Deacetylase Complex
- NuRD Histone Deacetylase Complex
- Nucleosome Remodeling and Deacetylase Complex
- NuRD Complex
- Complex, NuRD
- Histone Deacetylase Complex MI-2
- Histone Deacetylase Complex MI 2
- Histone Deacetylase Complex NuRD
|
Below are MeSH descriptors whose meaning is more general than "Mi-2 Nucleosome Remodeling and Deacetylase Complex".
Below are MeSH descriptors whose meaning is more specific than "Mi-2 Nucleosome Remodeling and Deacetylase Complex".
This graph shows the total number of publications written about "Mi-2 Nucleosome Remodeling and Deacetylase Complex" by people in this website by year, and whether "Mi-2 Nucleosome Remodeling and Deacetylase Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Mi-2 Nucleosome Remodeling and Deacetylase Complex" by people in Profiles.
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The Chd4 subunit of the NuRD complex regulates Pdx1-controlled genes involved in ?-cell function. J Mol Endocrinol. 2022 06 14; 69(2):329-341.
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De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms. Am J Hum Genet. 2016 Oct 06; 99(4):934-941.
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ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state. Cell Rep. 2014 Jan 30; 6(2):313-24.
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The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers. Cell Rep. 2014 Jan 30; 6(2):325-35.
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The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res. 2011 Feb; 21(2):275-89.
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15-LOX-1 transcription suppression through the NuRD complex in colon cancer cells. Oncogene. 2009 Mar 26; 28(12):1496-505.
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MTA1-mediated transcriptional repression of BRCA1 tumor suppressor gene. Oncogene. 2008 Mar 27; 27(14):1971-80.
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Emerging roles of MTA family members in human cancers. Semin Oncol. 2003 Oct; 30(5 Suppl 16):30-7.
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Differential association of products of alternative transcripts of the candidate tumor suppressor ING1 with the mSin3/HDAC1 transcriptional corepressor complex. J Biol Chem. 2001 Mar 23; 276(12):8734-9.