Sin3 Histone Deacetylase and Corepressor Complex
"Sin3 Histone Deacetylase and Corepressor Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multisubunit enzyme complex that regulates GENETIC TRANSCRIPTION by deacetylating the HISTONE residues of NUCLEOSOMES.
Descriptor ID |
D056264
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MeSH Number(s) |
D08.811.277.087.520.750 D08.811.600.795 D12.776.930.780.625.750
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Concept/Terms |
Sin3 Histone Deacetylase and Corepressor Complex- Sin3 Histone Deacetylase and Corepressor Complex
- SIN-3 Histone Deacetylase Complex
- SIN 3 Histone Deacetylase Complex
- SIN3 Complex
- SIN3 Histone Deacetylase Complex
- Sin3 Corepressor Complex
- Corepressor Complex, Sin3
- Sin3-Histone Deacetylase (HDAC) Corepressor Complex
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Below are MeSH descriptors whose meaning is more general than "Sin3 Histone Deacetylase and Corepressor Complex".
Below are MeSH descriptors whose meaning is more specific than "Sin3 Histone Deacetylase and Corepressor Complex".
This graph shows the total number of publications written about "Sin3 Histone Deacetylase and Corepressor Complex" by people in this website by year, and whether "Sin3 Histone Deacetylase and Corepressor Complex" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1998 | 0 | 1 | 1 |
2001 | 0 | 2 | 2 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2012 | 0 | 2 | 2 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sin3 Histone Deacetylase and Corepressor Complex" by people in Profiles.
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Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1a Degradation at the ASS1 promoter for ASS1 Derepression. Sci Rep. 2017 09 07; 7(1):10814.
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Distinct requirements for Sin3a in perinatal male gonocytes and differentiating spermatogonia. Dev Biol. 2013 Jan 01; 373(1):83-94.
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Minireview: nuclear receptor and coregulator proteomics--2012 and beyond. Mol Endocrinol. 2012 Oct; 26(10):1646-50.
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Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor alpha gene expression via p38MAPK/CK2 signaling in human breast cancer cells. FASEB J. 2011 Oct; 25(10):3695-707.
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Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug; 28(8):1424-34.
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Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression. Mol Cell Biol. 2008 Mar; 28(6):1988-98.
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mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival. Genes Dev. 2005 Jul 01; 19(13):1581-95.
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Loss of Sin3/Rpd3 histone deacetylase restores the DNA damage response in checkpoint-deficient strains of Saccharomyces cerevisiae. Mol Cell Biol. 2003 Jul; 23(13):4522-31.
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Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex. Mol Cell Biol. 2002 Apr; 22(8):2743-50.
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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature. 2001 Oct 18; 413(6857):739-43.