Prostaglandin-Endoperoxide Synthases
"Prostaglandin-Endoperoxide Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
| Descriptor ID |
D011451
|
| MeSH Number(s) |
D08.811.600.720 D08.811.682.690.708.715
|
| Concept/Terms |
Prostaglandin-Endoperoxide Synthases- Prostaglandin-Endoperoxide Synthases
- Prostaglandin Endoperoxide Synthases
- Synthases, Prostaglandin-Endoperoxide
- Prostaglandin-Endoperoxide Synthase
- Synthase, Prostaglandin-Endoperoxide
- Cyclooxygenase
- Cyclooxygenases
- Fatty Acid Cyclo-Oxygenase
- Cyclo-Oxygenase, Fatty Acid
- Fatty Acid Cyclo Oxygenase
- Hydroperoxide Cyclase
- Cyclase, Hydroperoxide
- PGH Synthase
- Synthase, PGH
- PGH2 Synthetase
- Synthetase, PGH2
- Prostaglandin Cyclo-Oxygenase
- Cyclo-Oxygenase, Prostaglandin
- Prostaglandin Cyclo Oxygenase
- Prostaglandin Cyclooxygenase
- Cyclooxygenase, Prostaglandin
- Prostaglandin Endoperoxide Synthetase
- Endoperoxide Synthetase, Prostaglandin
- Synthetase, Prostaglandin Endoperoxide
- Prostaglandin G-H Synthase
- G-H Synthase, Prostaglandin
- Prostaglandin G H Synthase
- Synthase, Prostaglandin G-H
- Prostaglandin H Synthase
- Synthase, Prostaglandin H
- Prostaglandin H2 Synthetase
- Synthetase, Prostaglandin H2
- Prostaglandin Synthase
- Synthase, Prostaglandin
- Prostaglandin Synthetase
- Synthetase, Prostaglandin
- Arachidonic Acid Cyclooxygenase
- Cyclooxygenase, Arachidonic Acid
- Cyclo-Oxygenase
- Cyclo Oxygenase
|
Below are MeSH descriptors whose meaning is more general than "Prostaglandin-Endoperoxide Synthases".
Below are MeSH descriptors whose meaning is more specific than "Prostaglandin-Endoperoxide Synthases".
This graph shows the total number of publications written about "Prostaglandin-Endoperoxide Synthases" by people in this website by year, and whether "Prostaglandin-Endoperoxide Synthases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 2 | 2 | 4 |
| 1997 | 4 | 0 | 4 |
| 1998 | 3 | 0 | 3 |
| 1999 | 7 | 4 | 11 |
| 2000 | 7 | 7 | 14 |
| 2001 | 10 | 8 | 18 |
| 2002 | 15 | 13 | 28 |
| 2003 | 14 | 19 | 33 |
| 2004 | 14 | 11 | 25 |
| 2005 | 13 | 9 | 22 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 3 | 3 |
| 2010 | 0 | 3 | 3 |
| 2011 | 2 | 1 | 3 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Prostaglandin-Endoperoxide Synthases" by people in Profiles.
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The inflammatory signature in monocytes of Sj?gren's syndrome and systemic lupus erythematosus, revealed by the integrated Reactome and drug target analysis. Genes Genomics. 2022 10; 44(10):1215-1229.
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Redirecting thromboxane A2 and prostacyclin biosyntheses from thrombotic to antithrombotic property by an Enzymelink. Future Med Chem. 2021 05; 13(9):765-768.
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Proteomics in gastroparesis: unique and overlapping protein signatures in diabetic and idiopathic gastroparesis. Am J Physiol Gastrointest Liver Physiol. 2019 11 01; 317(5):G716-G726.
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Bioactive lipid metabolism in platelet "first responder" and cancer biology. Cancer Metastasis Rev. 2018 09; 37(2-3):439-454.
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Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase. Bioorg Med Chem. 2017 02 01; 25(3):1202-1218.
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Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma. Gut. 2017 10; 66(10):1739-1747.
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Estrogen receptor-? and fetoplacental endothelial prostanoid biosynthesis: a link to clinically demonstrated fetal growth restriction. J Clin Endocrinol Metab. 2011 Oct; 96(10):E1558-67.
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Cyclooxygenase reaction mechanism of prostaglandin H synthase from deuterium kinetic isotope effects. J Inorg Biochem. 2011 Mar; 105(3):382-90.
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Cyclooxygenase reaction mechanism of PGHS--evidence for a reversible transition between a pentadienyl radical and a new tyrosyl radical by nitric oxide trapping. J Inorg Biochem. 2011 Mar; 105(3):356-65.
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Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophages. Arterioscler Thromb Vasc Biol. 2010 Oct; 30(10):2014-21.