Heme Oxygenase (Decyclizing)
"Heme Oxygenase (Decyclizing)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt.
| Descriptor ID |
D006419
|
| MeSH Number(s) |
D08.811.682.690.708.410
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Heme Oxygenase (Decyclizing)".
Below are MeSH descriptors whose meaning is more specific than "Heme Oxygenase (Decyclizing)".
This graph shows the total number of publications written about "Heme Oxygenase (Decyclizing)" by people in this website by year, and whether "Heme Oxygenase (Decyclizing)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heme Oxygenase (Decyclizing)" by people in Profiles.
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Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance. Nat Commun. 2021 09 06; 12(1):5270.
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Crystal structure of HugZ, a novel heme oxygenase from Helicobacter pylori. J Biol Chem. 2011 Jan 14; 286(2):1537-44.
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Ketamine-induced hepatoprotection: the role of heme oxygenase-1. Am J Physiol Gastrointest Liver Physiol. 2009 Jun; 296(6):G1360-9.
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Crystallization and preliminary crystallographic studies of Helicobacter pylori HugZ, a novel haem oxygenase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Apr 01; 65(Pt 4):376-8.
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Functional identification of HugZ, a heme oxygenase from Helicobacter pylori. BMC Microbiol. 2008 Dec 17; 8:226.
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Sustained normalization of high blood pressure in spontaneously hypertensive rats by implanted hemin pump. Hypertension. 2006 Oct; 48(4):685-92.
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Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide. Circulation. 1995 May 01; 91(9):2306-9.