"Histone Deacetylase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histone deacetylase subtype that is found along with HISTONE DEACETYLASE 1; RETINOBLASTOMA-BINDING PROTEIN 4; and RETINOBLASTOMA-BINDING PROTEIN 7 as core components of histone deacetylase complexes.
| Descriptor ID |
D056464
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| MeSH Number(s) |
D08.811.277.087.520.500.200 D08.811.277.087.520.750.200 D08.811.600.620.200 D08.811.600.795.200
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histone Deacetylase 2".
Below are MeSH descriptors whose meaning is more specific than "Histone Deacetylase 2".
This graph shows the total number of publications written about "Histone Deacetylase 2" by people in this website by year, and whether "Histone Deacetylase 2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 4 | 4 |
| 2010 | 1 | 4 | 5 |
| 2011 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 0 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Histone Deacetylase 2" by people in Profiles.
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Key epigenetic and signaling factors in the formation and maintenance of the blood-brain barrier. Elife. 2024 Dec 13; 12.
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Nerve injury augments Cacna2d1 transcription via CK2-mediated phosphorylation of the histone deacetylase HDAC2 in dorsal root ganglia. J Biol Chem. 2024 Nov; 300(11):107848.
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A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression. Cancer Lett. 2023 09 01; 571:216333.
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HDAC2 in Primary Sensory Neurons Constitutively Restrains Chronic Pain by Repressing a2d-1 Expression and Associated NMDA Receptor Activity. J Neurosci. 2022 11 30; 42(48):8918-8935.
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CD5L attenuates allergic airway inflammation by expanding CD11chigh alveolar macrophages and inhibiting NLRP3 inflammasome activation via HDAC2. Immunology. 2022 11; 167(3):384-397.
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Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2. Mol Psychiatry. 2021 08; 26(8):4066-4084.
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KRCC1: A potential therapeutic target in ovarian cancer. FASEB J. 2020 02; 34(2):2287-2300.
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Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma. Blood. 2019 01 24; 133(4):306-318.
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SUMOylation of ROR-?t inhibits IL-17 expression and inflammation via HDAC2. Nat Commun. 2018 10 30; 9(1):4515.
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Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1a Degradation at the ASS1 promoter for ASS1 Derepression. Sci Rep. 2017 09 07; 7(1):10814.