"Histone Deacetylase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histone deacetylase subtype that is found along with HISTONE DEACETYLASE 1; RETINOBLASTOMA-BINDING PROTEIN 4; and RETINOBLASTOMA-BINDING PROTEIN 7 as core components of histone deacetylase complexes.
| Descriptor ID |
D056464
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| MeSH Number(s) |
D08.811.277.087.520.500.200 D08.811.277.087.520.750.200 D08.811.600.620.200 D08.811.600.795.200
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histone Deacetylase 2".
Below are MeSH descriptors whose meaning is more specific than "Histone Deacetylase 2".
This graph shows the total number of publications written about "Histone Deacetylase 2" by people in this website by year, and whether "Histone Deacetylase 2" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Histone Deacetylase 2" by people in Profiles.
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ADNP Exhibits Methyltransferase Activity in Overexpression Systems and Modulates DNA and Histone Methylation. Autism Res. 2025 Nov; 18(11):2174-2191.
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A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression. Cancer Lett. 2023 09 01; 571:216333.
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Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2. Mol Psychiatry. 2021 08; 26(8):4066-4084.
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Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. Hum Mol Genet. 2017 04 01; 26(7):1305-1317.
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Beta-adrenergic signaling promotes tumor angiogenesis and prostate cancer progression through HDAC2-mediated suppression of thrombospondin-1. Oncogene. 2017 03; 36(11):1525-1536.
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Loss of histone deacetylase 2 improves working memory and accelerates extinction learning. J Neurosci. 2013 Apr 10; 33(15):6401-11.
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Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway. Dev Cell. 2013 Feb 25; 24(4):345-58.
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The effects of cigarette smoke on airway inflammation in asthma and COPD: therapeutic implications. Respir Med. 2012 Mar; 106(3):319-28.
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The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res. 2011 Feb; 21(2):275-89.
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Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin. J Nutr Biochem. 2011 May; 22(5):450-8.