HSP40 Heat-Shock Proteins
"HSP40 Heat-Shock Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of heat-shock proteins that contain a 70 amino-acid consensus sequence known as the J domain. The J domain of HSP40 heat shock proteins interacts with HSP70 HEAT-SHOCK PROTEINS. HSP40 heat-shock proteins play a role in regulating the ADENOSINE TRIPHOSPHATASES activity of HSP70 heat-shock proteins.
| Descriptor ID |
D050956
|
| MeSH Number(s) |
D12.776.580.216.292
|
| Concept/Terms |
HSP40 Heat-Shock Proteins- HSP40 Heat-Shock Proteins
- HSP40 Heat Shock Proteins
- Heat-Shock Proteins, HSP40
- Proteins, HSP40 Heat-Shock
- Heat Shock Protein 40 Family
- Heat-Shock Protein 40
- Heat Shock Protein 40
- HSP40 Proteins
- DnaJ Proteins
- HSP40 Protein Family
- Heat-Shock Proteins 40
- Heat Shock Proteins 40
|
Below are MeSH descriptors whose meaning is more general than "HSP40 Heat-Shock Proteins".
Below are MeSH descriptors whose meaning is more specific than "HSP40 Heat-Shock Proteins".
This graph shows the total number of publications written about "HSP40 Heat-Shock Proteins" by people in this website by year, and whether "HSP40 Heat-Shock Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "HSP40 Heat-Shock Proteins" by people in Profiles.
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GmHSP40.1, a nuclear-localized soybean J domain protein, participates in regulation of flowering time through interacting with EMF1 and JMJ14. Plant Sci. 2025 Mar; 352:112342.
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Sodium Butyrate Inhibits the Malignant Proliferation of Colon Cancer Cells via the miR-183/DNAJB4 Axis. Biochem Genet. 2024 Oct; 62(5):4174-4190.
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Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer. Cancer Res. 2018 07 15; 78(14):4022-4035.
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Mapping interactions with the chaperone network reveals factors that protect against tau aggregation. Nat Struct Mol Biol. 2018 05; 25(5):384-393.
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Structural determinants for protein unfolding and translocation by the Hsp104 protein disaggregase. Biosci Rep. 2017 12 22; 37(6).
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Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy. Cell Rep. 2015 Aug 18; 12(7):1169-83.
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Modulation of the unfolded protein response during hepatocyte and cardiomyocyte apoptosis in trauma/hemorrhagic shock. Sci Rep. 2013; 3:1187.
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The M-domain controls Hsp104 protein remodeling activity in an Hsp70/Hsp40-dependent manner. J Mol Biol. 2010 Sep 10; 402(1):30-7.
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Patterns of GRP78 and MTJ1 expression in primary cutaneous malignant melanoma. Mod Pathol. 2010 Jan; 23(1):134-43.
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From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease. Curr Opin Neurol. 2003 Aug; 16(4):443-9.