"Dystonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A plakin characterized by repeat sequences homologous to SPECTRIN and PLECTIN and C-terminal EF HAND MOTIFS. It functions as an integrator of INTERMEDIATE FILAMENTS, ACTIN and MICROTUBULES in cytoskeleton networks. It is required for anchoring intermediate filaments to the actin cytoskeleton in neural and muscle cells as well as anchoring KERATIN-containing intermediate filaments to HEMIDESMOSOMES in EPITHELIAL CELLS.
| Descriptor ID |
D000071821
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| MeSH Number(s) |
D12.776.220.790.625
|
| Concept/Terms |
Dystonin- Dystonin
- Bullous Pemphigoid Antigen 1
- 230-240 kDa Bullous Pemphigoid Antigen
- 230 240 kDa Bullous Pemphigoid Antigen
- Hemidesmosomal Plaque Protein
- 230 kDa Bullous Pemphigoid Antigen
|
Below are MeSH descriptors whose meaning is more general than "Dystonin".
Below are MeSH descriptors whose meaning is more specific than "Dystonin".
This graph shows the total number of publications written about "Dystonin" by people in this website by year, and whether "Dystonin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dystonin" by people in Profiles.
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Expanding the phenotype of DST-related disorder: A case report suggesting a genotype/phenotype correlation. Am J Med Genet A. 2017 Oct; 173(10):2743-2746.
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A recombinant tail-less integrin beta 4 subunit disrupts hemidesmosomes, but does not suppress alpha 6 beta 4-mediated cell adhesion to laminins. J Cell Biol. 1995 Apr; 129(2):473-87.
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Chromosomal localization of mouse bullous pemphigoid antigens. BPAG1 and BPAG2: identification of a new region of homology between mouse and human chromosomes. Genomics. 1993 Jan; 15(1):180-1.