"Lysine-tRNA Ligase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that activates lysine with its specific transfer RNA. EC 6.1.1.6.
| Descriptor ID |
D008250
|
| MeSH Number(s) |
D08.811.464.263.200.550
|
| Concept/Terms |
Lysine-tRNA Ligase- Lysine-tRNA Ligase
- Ligase, Lysine-tRNA
- Lysine tRNA Ligase
- Lys-tRNA Ligase
- Ligase, Lys-tRNA
- Lys tRNA Ligase
- Lysyl-tRNA Synthetase
- Lysyl tRNA Synthetase
- Synthetase, Lysyl-tRNA
- Lysyl T RNA Synthetase
|
Below are MeSH descriptors whose meaning is more general than "Lysine-tRNA Ligase".
Below are MeSH descriptors whose meaning is more specific than "Lysine-tRNA Ligase".
This graph shows the total number of publications written about "Lysine-tRNA Ligase" by people in this website by year, and whether "Lysine-tRNA Ligase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lysine-tRNA Ligase" by people in Profiles.
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Antibody Deficiency in Patients with Biallelic KARS1 Mutations. J Clin Immunol. 2023 11; 43(8):2115-2125.
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Bi-allelic KARS1 pathogenic variants affecting functions of cytosolic and mitochondrial isoforms are associated with a progressive and multisystem disease. Hum Mutat. 2021 06; 42(6):745-761.
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Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction. Nat Chem Biol. 2014 Jan; 10(1):29-34.
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Mutations in KARS, encoding lysyl-tRNA synthetase, cause autosomal-recessive nonsyndromic hearing impairment DFNB89. Am J Hum Genet. 2013 Jul 11; 93(1):132-40.
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Compound heterozygosity for loss-of-function lysyl-tRNA synthetase mutations in a patient with peripheral neuropathy. Am J Hum Genet. 2010 Oct 08; 87(4):560-6.