Amino Acyl-tRNA Synthetases
"Amino Acyl-tRNA Synthetases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of enzymes that aminoacylate AMINO ACID-SPECIFIC TRANSFER RNA with their corresponding AMINO ACIDS.
| Descriptor ID |
D000604
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| MeSH Number(s) |
D08.811.464.263.200
|
| Concept/Terms |
Amino Acyl-tRNA Synthetases- Amino Acyl-tRNA Synthetases
- Acyl-tRNA Synthetases, Amino
- Amino Acyl tRNA Synthetases
- Synthetases, Amino Acyl-tRNA
- Amino Acyl-tRNA Ligases
- Acyl-tRNA Ligases, Amino
- Amino Acyl tRNA Ligases
- Ligases, Amino Acyl-tRNA
- tRNA Synthetase
- Synthetase, tRNA
- Aminoacyl-tRNA Synthetase
- Aminoacyl tRNA Synthetase
- Synthetase, Aminoacyl-tRNA
- Transfer RNA Synthetase
- RNA Synthetase, Transfer
- Synthetase, Transfer RNA
- Amino Acyl T RNA Synthetases
- Aminoacyl Transfer RNA Synthetase
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Below are MeSH descriptors whose meaning is more general than "Amino Acyl-tRNA Synthetases".
Below are MeSH descriptors whose meaning is more specific than "Amino Acyl-tRNA Synthetases".
This graph shows the total number of publications written about "Amino Acyl-tRNA Synthetases" by people in this website by year, and whether "Amino Acyl-tRNA Synthetases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 2 | 0 | 2 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Amino Acyl-tRNA Synthetases" by people in Profiles.
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The mARS complex: a critical mediator of immune regulation and homeostasis. Front Immunol. 2024; 15:1423510.
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Intracranial calcifications simulating Aicardi-Gouti?res syndrome in PARS2-related mitochondrial disease. Am J Med Genet A. 2024 07; 194(7):e63589.
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A first-in-class leucyl-tRNA synthetase inhibitor, ganfeborole, for rifampicin-susceptible tuberculosis: a phase 2a open-label, randomized trial. Nat Med. 2024 Mar; 30(3):896-904.
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Coordination between aminoacylation and editing to protect against proteotoxicity. Nucleic Acids Res. 2023 10 27; 51(19):10606-10618.
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Antibody Deficiency in Patients with Biallelic KARS1 Mutations. J Clin Immunol. 2023 11; 43(8):2115-2125.
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Metabolic impact of pathogenic variants in the mitochondrial glutamyl-tRNA synthetase EARS2. J Inherit Metab Dis. 2021 07; 44(4):949-960.
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MHC class I and II peptide homology regulates the cellular immune response. FASEB J. 2020 06; 34(6):8082-8101.
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Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells. Proc Natl Acad Sci U S A. 2019 07 16; 116(29):14614-14619.
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FARS2 deficiency; new cases, review of clinical, biochemical, and molecular spectra, and variants interpretation based on structural, functional, and evolutionary significance. Mol Genet Metab. 2018 11; 125(3):281-291.
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Antisynthetase syndrome: Pulmonary computed tomography findings of adult patients with antibodies to aminoacyl-tRNA synthetases. Eur J Radiol. 2016 Aug; 85(8):1421-6.