"Th1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of helper-inducer T-lymphocytes which synthesize and secrete INTERLEUKIN-2; INTERFERON-GAMMA; and INTERLEUKIN-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.
| Descriptor ID |
D018417
|
| MeSH Number(s) |
A11.118.637.555.567.550.500.400.900 A11.118.637.555.567.569.200.400.900 A11.118.637.555.567.569.500.400.900 A15.145.229.637.555.567.550.500.400.500 A15.145.229.637.555.567.569.200.400.500 A15.145.229.637.555.567.569.500.400.500 A15.382.490.555.567.550.500.400.900 A15.382.490.555.567.569.200.400.900 A15.382.490.555.567.569.500.400.900
|
| Concept/Terms |
Th1 Cells- Th1 Cells
- Cell, Th1
- Cells, Th1
- Th1 Cell
- TH-1 Cells
- Cell, TH-1
- Cells, TH-1
- TH 1 Cells
- TH-1 Cell
- T Helper 1 Cells
- Type 1 Helper T Cells
|
Below are MeSH descriptors whose meaning is more general than "Th1 Cells".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
- Th1 Cells [A11.118.637.555.567.550.500.400.900]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
- Th1 Cells [A11.118.637.555.567.569.200.400.900]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
- Th1 Cells [A11.118.637.555.567.569.500.400.900]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
- Th1 Cells [A15.145.229.637.555.567.550.500.400.500]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
- Th1 Cells [A15.145.229.637.555.567.569.200.400.500]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
- Th1 Cells [A15.145.229.637.555.567.569.500.400.500]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
- Th1 Cells [A15.382.490.555.567.550.500.400.900]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
- Th1 Cells [A15.382.490.555.567.569.200.400.900]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
- Th1 Cells [A15.382.490.555.567.569.500.400.900]
Below are MeSH descriptors whose meaning is more specific than "Th1 Cells".
This graph shows the total number of publications written about "Th1 Cells" by people in this website by year, and whether "Th1 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 3 | 4 |
| 2002 | 2 | 2 | 4 |
| 2003 | 2 | 1 | 3 |
| 2004 | 2 | 1 | 3 |
| 2005 | 0 | 3 | 3 |
| 2006 | 2 | 2 | 4 |
| 2007 | 4 | 2 | 6 |
| 2008 | 1 | 1 | 2 |
| 2009 | 5 | 2 | 7 |
| 2010 | 3 | 2 | 5 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 1 | 3 |
| 2013 | 2 | 2 | 4 |
| 2014 | 0 | 4 | 4 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 2 | 4 |
| 2018 | 4 | 3 | 7 |
| 2019 | 2 | 2 | 4 |
| 2020 | 0 | 4 | 4 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 2 | 3 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
| 2026 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Th1 Cells" by people in Profiles.
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Immunological insights into why pertussis continues to be endemic. Hum Vaccin Immunother. 2026 Dec; 22(1):2692306.
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Mucosal Vaccination With Recombinant Tm-WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice. Front Immunol. 2022; 13:800295.
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CD11c participates in triggering acute graft-versus-host disease during bone marrow transplantation. Immunology. 2021 09; 164(1):148-160.
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A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection. PLoS Negl Trop Dis. 2019 05; 13(5):e0007413.
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Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice. Hum Vaccin Immunother. 2019; 15(1):210-219.
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IL-21 Selectively Protects CD62L+ NKT Cells and Enhances Their Effector Functions for Adoptive Immunotherapy. J Immunol. 2018 10 01; 201(7):2141-2153.
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Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes. J Immunol. 2018 07 01; 201(1):124-133.
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Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017 04 13; 544(7649):250-254.
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Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation. J Allergy Clin Immunol. 2017 May; 139(5):1629-1640.e2.
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A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease. Hum Vaccin Immunother. 2016 04 02; 12(4):976-87.