Organic Cation Transporter 2
"Organic Cation Transporter 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic cation transporter consisting of twelve transmembrane domains and expressed primarily in the kidney. It transports a wide range of metabolites, drugs, and neurotransmitters from the blood to the KIDNEY TUBULES, including DOPAMINE; SEROTONIN; CHOLINE; and CISPLATIN.
| Descriptor ID |
D000075102
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| MeSH Number(s) |
D12.776.157.530.450.250.812.625 D12.776.157.530.937.612.625 D12.776.543.585.450.250.812.625 D12.776.543.585.937.701.625
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Organic Cation Transporter 2".
Below are MeSH descriptors whose meaning is more specific than "Organic Cation Transporter 2".
This graph shows the total number of publications written about "Organic Cation Transporter 2" by people in this website by year, and whether "Organic Cation Transporter 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Organic Cation Transporter 2" by people in Profiles.
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An integrative approach to cisplatin chronic toxicities in mice reveals importance of organic cation-transporter-dependent protein networks for renoprotection. Arch Toxicol. 2019 10; 93(10):2835-2848.
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Two unrelated children with overlapping 6q25.3 deletions, motor speech disorders, and language delays. Am J Med Genet A. 2017 Oct; 173(10):2659-2669.
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Renal organic cation and nucleoside transport. Biochem Pharmacol. 2002 Jul 15; 64(2):185-90.
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Role of organic cation transporters in the renal secretion of nucleosides. Biochem Pharmacol. 2000 Jul 15; 60(2):215-9.
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A nucleoside-sensitive organic cation transporter in opossum kidney cells. Am J Physiol. 1999 02; 276(2):F323-8.
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A transfected cell model for the renal toxin transporter, rOCT2. Toxicol Sci. 1999 Feb; 47(2):181-6.