"Base Pair Mismatch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The presence of an uncomplimentary base in double-stranded DNA caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES).
| Descriptor ID |
D020137
|
| MeSH Number(s) |
G05.365.590.060
|
| Concept/Terms |
Base Pair Mismatch- Base Pair Mismatch
- Mismatch, Base Pair
- Base Pair Mismatches
- Mismatches, Base Pair
|
Below are MeSH descriptors whose meaning is more general than "Base Pair Mismatch".
Below are MeSH descriptors whose meaning is more specific than "Base Pair Mismatch".
This graph shows the total number of publications written about "Base Pair Mismatch" by people in this website by year, and whether "Base Pair Mismatch" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 2 | 3 | 5 |
| 2000 | 1 | 6 | 7 |
| 2001 | 1 | 7 | 8 |
| 2002 | 3 | 1 | 4 |
| 2003 | 3 | 3 | 6 |
| 2004 | 2 | 5 | 7 |
| 2005 | 1 | 3 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 2 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Base Pair Mismatch" by people in Profiles.
-
Microsatellite Instability Assessment by Immunohistochemistry in Acute Myeloid Leukemia: A Reappraisal and Review of the Literature. Clin Lymphoma Myeloma Leuk. 2022 06; 22(6):e386-e391.
-
Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study. Nat Biotechnol. 2021 09; 39(9):1129-1140.
-
Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations. Nucleic Acids Res. 2021 05 21; 49(9):5084-5094.
-
CRISPR/Cas9 can mediate high-efficiency off-target mutations in mice in vivo. Cell Death Dis. 2018 Oct 27; 9(11):1099.
-
DNA polymerase ? (POLQ), double-strand break repair, and cancer. DNA Repair (Amst). 2016 08; 44:22-32.
-
Stable gene targeting in human cells using single-strand oligonucleotides with modified bases. PLoS One. 2012; 7(5):e36697.
-
Microsatellite instability and DNA mismatch repair protein deficiency in Lynch syndrome colorectal polyps. Cancer Prev Res (Phila). 2012 Apr; 5(4):574-82.
-
CREST maps somatic structural variation in cancer genomes with base-pair resolution. Nat Methods. 2011 Jun 12; 8(8):652-4.
-
Flexibility promotes fidelity. Structure. 2009 May 13; 17(5):633-4.
-
Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses. J Biol Chem. 2008 Aug 01; 283(31):21382-93.