"Chromosomal Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.
| Descriptor ID |
D043171
|
| MeSH Number(s) |
C23.550.210.110 C23.550.362.180 G05.365.590.175.165 G05.370.180
|
| Concept/Terms |
Chromosomal Instability- Chromosomal Instability
- Chromosomal Instabilities
- Instabilities, Chromosomal
- Instability, Chromosomal
- Chromosome Instability
- Chromosome Instabilities
- Instabilities, Chromosome
- Instability, Chromosome
Chromosome Stability- Chromosome Stability
- Chromosome Stabilities
- Stabilities, Chromosome
- Stability, Chromosome
- Chromosomal Stability
- Chromosomal Stabilities
- Stabilities, Chromosomal
- Stability, Chromosomal
|
Below are MeSH descriptors whose meaning is more general than "Chromosomal Instability".
Below are MeSH descriptors whose meaning is more specific than "Chromosomal Instability".
This graph shows the total number of publications written about "Chromosomal Instability" by people in this website by year, and whether "Chromosomal Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 3 | 0 | 3 |
| 2004 | 3 | 3 | 6 |
| 2005 | 6 | 4 | 10 |
| 2006 | 4 | 0 | 4 |
| 2007 | 4 | 1 | 5 |
| 2008 | 5 | 2 | 7 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 2 | 4 |
| 2011 | 2 | 2 | 4 |
| 2012 | 0 | 1 | 1 |
| 2013 | 3 | 2 | 5 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 3 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 0 | 3 | 3 |
| 2018 | 3 | 1 | 4 |
| 2019 | 3 | 3 | 6 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 4 | 5 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Chromosomal Instability" by people in Profiles.
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Chromosomal instability is associated with prognosis and efficacy of bevacizumab after resection of colorectal cancer liver metastasis. Ann Med. 2024 Dec; 56(1):2396559.
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Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response. Nat Commun. 2024 Jan 02; 15(1):180.
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Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors. Cell. 2023 12 07; 186(25):5620-5637.e16.
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Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer. Nat Cancer. 2023 07; 4(7):984-1000.
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The Role of Non-Coding RNAs in Chromosomal Instability in Cancer. J Pharmacol Exp Ther. 2023 01; 384(1):10-19.
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APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis. Nat Cancer. 2021 12; 2(12):1338-1356.
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Serial assessment of measurable residual disease in medulloblastoma liquid biopsies. Cancer Cell. 2021 11 08; 39(11):1519-1530.e4.
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DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability. EMBO J. 2021 11 02; 40(21):e104543.
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Chromosomal instability by mutations in the novel minor spliceosome component CENATAC. EMBO J. 2021 07 15; 40(14):e106536.
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Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas. Nat Commun. 2021 01 29; 12(1):687.