Micronuclei, Chromosome-Defective
"Micronuclei, Chromosome-Defective" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Defective nuclei produced during the TELOPHASE of MITOSIS or MEIOSIS by lagging CHROMOSOMES or chromosome fragments derived from spontaneous or experimentally induced chromosomal structural changes.
| Descriptor ID |
D048629
|
| MeSH Number(s) |
A11.284.430.106.570 A11.284.430.214.190.875.117.570 C23.550.210.570 G05.365.590.175.570
|
| Concept/Terms |
Micronuclei, Chromosome-Defective- Micronuclei, Chromosome-Defective
- Chromosome-Defective Micronucleus
- Micronuclei, Chromosome Defective
- Micronucleus, Chromosome-Defective
- Micronucleus, Chromosome Defective
- Chromosome-Defective Micronuclei
- Chromosome Defective Micronuclei
Micronuclei, Genotoxicant-Induced- Micronuclei, Genotoxicant-Induced
- Genotoxicant-Induced Micronucleus
- Micronuclei, Genotoxicant Induced
- Micronucleus, Genotoxicant-Induced
- Genotoxicant-Induced Micronuclei
- Genotoxicant Induced Micronuclei
|
Below are MeSH descriptors whose meaning is more general than "Micronuclei, Chromosome-Defective".
Below are MeSH descriptors whose meaning is more specific than "Micronuclei, Chromosome-Defective".
This graph shows the total number of publications written about "Micronuclei, Chromosome-Defective" by people in this website by year, and whether "Micronuclei, Chromosome-Defective" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Micronuclei, Chromosome-Defective" by people in Profiles.
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Disruption of DNA polymerase ? engages an innate immune response. Cell Rep. 2021 02 23; 34(8):108775.
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Mechanisms of nuclear content loading to exosomes. Sci Adv. 2019 11; 5(11):eaax8849.
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SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma. Cancer Res. 2018 06 15; 78(12):3135-3146.
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Frequencies of micronucleated reticulocytes, a dosimeter of DNA double-strand breaks, in infants receiving computed tomography or cardiac catheterization. Mutat Res Genet Toxicol Environ Mutagen. 2017 Aug; 820:8-18.
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Double minute chromosomes in acute myeloid leukemia, myelodysplastic syndromes, and chronic myelomonocytic leukemia are associated with micronuclei, MYC or MLL amplification, and complex karyotype. Cancer Genet. 2016 Jul-Aug; 209(7-8):313-20.
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T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice. Mutagenesis. 2013 May; 28(3):263-70.
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Microcystin-LR, a protein phosphatase inhibitor, induces alterations in mitotic chromatin and microtubule organization leading to the formation of micronuclei in Vicia faba. Ann Bot. 2012 Sep; 110(4):797-808.
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DNA breaks and chromosome pulverization from errors in mitosis. Nature. 2012 Jan 18; 482(7383):53-8.
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Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning. Angle Orthod. 2012 Jul; 82(4):585-90.
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PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution. EMBO J. 2011 Jul 08; 30(16):3309-21.