"Ochronosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).
| Descriptor ID |
D009794
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| MeSH Number(s) |
C23.550.744
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ochronosis".
Below are MeSH descriptors whose meaning is more specific than "Ochronosis".
This graph shows the total number of publications written about "Ochronosis" by people in this website by year, and whether "Ochronosis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ochronosis" by people in Profiles.
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Severe Aortic Valve Stenosis Due to Alkaptonuric Ochronosis. Semin Cardiothorac Vasc Anesth. 2017 Dec; 21(4):364-366.
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Metal-induced granule deposition with pseudoochronosis. J Am Acad Dermatol. 2010 Aug; 63(2):357-9.
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Ochronosis in differential diagnosis of patients with chronic backache: a review of the literature. Rheumatol Int. 2007 Nov; 28(1):61-4.
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Exogenous ochronosis resulting from quinine injections. J Am Acad Dermatol. 1986 Aug; 15(2 Pt 2):357-61.