Clustered Regularly Interspaced Short Palindromic Repeats
"Clustered Regularly Interspaced Short Palindromic Repeats" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems.
| Descriptor ID |
D064112
|
| MeSH Number(s) |
G02.111.570.080.708.800.325.500 G05.360.080.708.800.325.500 G05.360.340.024.850.069
|
| Concept/Terms |
Clustered Regularly Interspaced Short Palindromic Repeats- Clustered Regularly Interspaced Short Palindromic Repeats
- CRISPRs
- CRISPR
- CRISPR Sequences
- CRISPR Sequence
- Sequence, CRISPR
- Sequences, CRISPR
- Clustered Regularly Interspaced Short Palindromic Repeat
- CRISPR Elements
- CRISPR Element
- Element, CRISPR
- Elements, CRISPR
CRISPR Spacers- CRISPR Spacers
- CRISPR Spacer
- Spacer, CRISPR
- Spacers, CRISPR
- CRISPR Spacer Sequences
- CRISPR Spacer Sequence
- Sequence, CRISPR Spacer
- Sequences, CRISPR Spacer
- Spacer Sequence, CRISPR
- Spacer Sequences, CRISPR
CRISPR-Cas Loci- CRISPR-Cas Loci
- CRISPR Cas Loci
- CRISPR-Cas Locus
- Loci, CRISPR-Cas
- Locus, CRISPR-Cas
CRISPR Loci- CRISPR Loci
- Loci, CRISPR
- Locus, CRISPR
- CRISPR Clusters
- CRISPR Cluster
- Cluster, CRISPR
- Clusters, CRISPR
- CRISPR Locus
- CRISPR Arrays
- Array, CRISPR
- Arrays, CRISPR
- CRISPR Array
|
Below are MeSH descriptors whose meaning is more general than "Clustered Regularly Interspaced Short Palindromic Repeats".
Below are MeSH descriptors whose meaning is more specific than "Clustered Regularly Interspaced Short Palindromic Repeats".
This graph shows the total number of publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in this website by year, and whether "Clustered Regularly Interspaced Short Palindromic Repeats" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2015 | 3 | 0 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 5 | 3 | 8 |
| 2019 | 6 | 2 | 8 |
| 2020 | 3 | 6 | 9 |
| 2021 | 0 | 2 | 2 |
| 2022 | 2 | 2 | 4 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in Profiles.
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Identification of TUBB3 as an immunotherapy target in lung cancer by genome wide in vivo CRISPR screening. Neoplasia. 2025 02; 60:101100.
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A One-Step RPA-CRISPR Assay Using crRNA Based on Suboptimal Protospacer Adjacent Motif for Vibrio vulnificus Detection. Foodborne Pathog Dis. 2024 Jul; 21(7):458-466.
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Genome-wide CRISPR screen reveals the synthetic lethality between BCL2L1 inhibition and radiotherapy. Life Sci Alliance. 2024 04; 7(4).
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CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbon. JCI Insight. 2024 01 23; 9(2).
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CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants. Circulation. 2024 Apr 16; 149(16):1285-1297.
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Ultrasensitive one-pot detection of monkeypox virus with RPA and CRISPR in a sucrose-aided multiphase aqueous system. Microbiol Spectr. 2024 Jan 11; 12(1):e0226723.
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FACS-based genome-wide CRISPR screens define key regulators of DNA damage signaling pathways. Mol Cell. 2023 08 03; 83(15):2810-2828.e6.
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Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens. Proc Natl Acad Sci U S A. 2023 04 18; 120(16):e2220134120.
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Genome-Wide CRISPR Screens Reveal ZATT as a Synthetic Lethal Target of TOP2-Poison Etoposide That Can Act in a TDP2-Independent Pathway. Int J Mol Sci. 2023 Mar 31; 24(7).
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A Programmable In Vivo CRISPR Activation Model Elucidates the Oncogenic and Immunosuppressive Functions of MYC in Lung Adenocarcinoma. Cancer Res. 2022 08 03; 82(15):2761-2776.