Clustered Regularly Interspaced Short Palindromic Repeats
"Clustered Regularly Interspaced Short Palindromic Repeats" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems.
| Descriptor ID |
D064112
|
| MeSH Number(s) |
G02.111.570.080.708.800.325.500 G05.360.080.708.800.325.500 G05.360.340.024.850.069
|
| Concept/Terms |
Clustered Regularly Interspaced Short Palindromic Repeats- Clustered Regularly Interspaced Short Palindromic Repeats
- CRISPRs
- CRISPR
- CRISPR Sequences
- CRISPR Sequence
- Sequence, CRISPR
- Sequences, CRISPR
- Clustered Regularly Interspaced Short Palindromic Repeat
- CRISPR Elements
- CRISPR Element
- Element, CRISPR
- Elements, CRISPR
CRISPR Spacers- CRISPR Spacers
- CRISPR Spacer
- Spacer, CRISPR
- Spacers, CRISPR
- CRISPR Spacer Sequences
- CRISPR Spacer Sequence
- Sequence, CRISPR Spacer
- Sequences, CRISPR Spacer
- Spacer Sequence, CRISPR
- Spacer Sequences, CRISPR
CRISPR-Cas Loci- CRISPR-Cas Loci
- CRISPR Cas Loci
- CRISPR-Cas Locus
- Loci, CRISPR-Cas
- Locus, CRISPR-Cas
CRISPR Loci- CRISPR Loci
- Loci, CRISPR
- Locus, CRISPR
- CRISPR Clusters
- CRISPR Cluster
- Cluster, CRISPR
- Clusters, CRISPR
- CRISPR Locus
- CRISPR Arrays
- Array, CRISPR
- Arrays, CRISPR
- CRISPR Array
|
Below are MeSH descriptors whose meaning is more general than "Clustered Regularly Interspaced Short Palindromic Repeats".
Below are MeSH descriptors whose meaning is more specific than "Clustered Regularly Interspaced Short Palindromic Repeats".
This graph shows the total number of publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in this website by year, and whether "Clustered Regularly Interspaced Short Palindromic Repeats" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2015 | 4 | 0 | 4 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 3 | 3 |
| 2018 | 5 | 3 | 8 |
| 2019 | 9 | 4 | 13 |
| 2020 | 4 | 5 | 9 |
| 2021 | 0 | 2 | 2 |
| 2022 | 2 | 2 | 4 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in Profiles.
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CRISPR-AsCas12a and dAsCas12a-Mediated Gene Knockout and Knockdown in Clostridioides difficile. Methods Mol Biol. 2026; 3046:47-55.
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Personalized CRISPR knock-in cytokine gene therapy to remodel the tumor microenvironment and enhance CAR T cell therapy in solid tumors. Nat Commun. 2025 Dec 09; 16(1):10987.
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CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants. Circulation. 2024 Apr 16; 149(16):1285-1297.
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An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Elife. 2022 06 20; 11.
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CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study. Lancet Microbe. 2022 07; 3(7):e482-e492.
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A genome-scale gain-of-function CRISPR screen in CD8 T?cells identifies proline metabolism as a means to enhance CAR-T therapy. Cell Metab. 2022 04 05; 34(4):595-614.e14.
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A CRISPR toolbox for generating intersectional genetic mouse models for functional, molecular, and anatomical circuit mapping. BMC Biol. 2022 01 28; 20(1):28.
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Characterizing a Common CERS2 Polymorphism in a Mouse Model of Metabolic Disease and in Subjects from the Utah CAD Study. J Clin Endocrinol Metab. 2021 07 13; 106(8):e3098-e3109.
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A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases. Proc Natl Acad Sci U S A. 2021 06 08; 118(23).
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CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade. Cancer Discov. 2020 12; 10(12):1912-1933.