"omega-Agatoxin IVA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE.
| Descriptor ID |
D020867
|
| MeSH Number(s) |
D12.644.400.562 D12.776.093.249.500 D20.888.065.870.324.500 D23.946.833.065.870.324.500
|
| Concept/Terms |
omega-Agatoxin IVA- omega-Agatoxin IVA
- IVA, omega-Agatoxin
- omega Agatoxin IVA
- omega-Aga-IVA
- omega Aga IVA
|
Below are MeSH descriptors whose meaning is more general than "omega-Agatoxin IVA".
Below are MeSH descriptors whose meaning is more specific than "omega-Agatoxin IVA".
This graph shows the total number of publications written about "omega-Agatoxin IVA" by people in this website by year, and whether "omega-Agatoxin IVA" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "omega-Agatoxin IVA" by people in Profiles.
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Masking epilepsy by combining two epilepsy genes. Nat Neurosci. 2007 Dec; 10(12):1554-8.
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Therapeutically relevant concentrations of neomycin selectively inhibit P-type Ca2+ channels in rat striatum. Eur J Pharmacol. 2003 Feb 14; 461(2-3):105-11.
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The status of voltage-dependent calcium channels in alpha 1E knock-out mice. J Neurosci. 2000 Dec 01; 20(23):8566-71.
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Inhibition of synaptic transmission by neuropeptide Y in rat hippocampal area CA1: modulation of presynaptic Ca2+ entry. J Neurosci. 1997 Nov 01; 17(21):8169-77.
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Presynaptic inhibition of synaptic transmission in the rat hippocampus by activation of muscarinic receptors: involvement of presynaptic calcium influx. Br J Pharmacol. 1997 Oct; 122(3):511-9.
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Pharmacological identification of two types of presynaptic voltage-dependent calcium channels at CA3-CA1 synapses of the hippocampus. J Neurosci. 1994 Sep; 14(9):5613-22.