"Neurotensin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.
| Descriptor ID |
D009496
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| MeSH Number(s) |
D12.644.400.550 D12.776.631.650.550
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neurotensin".
Below are MeSH descriptors whose meaning is more specific than "Neurotensin".
This graph shows the total number of publications written about "Neurotensin" by people in this website by year, and whether "Neurotensin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurotensin" by people in Profiles.
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Improvement in blastocyst quality by neurotensin signaling via its receptors in bovine spermatozoa during in vitro fertilization. J Reprod Dev. 2019 Apr 12; 65(2):147-153.
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Exogenous neurotensin modulates sperm function in Japanese Black cattle. J Reprod Dev. 2016 Aug 25; 62(4):409-14.
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Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes. Diabetes. 2012 Jul; 61(7):1793-800.
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Differences in Ca(2+) signaling underlie age-specific effects of secretagogues on colonic Cl(-) transport. Am J Physiol Cell Physiol. 2001 Mar; 280(3):C646-58.
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Neurotensin-mediated activation of MAPK pathways and AP-1 binding in the human pancreatic cancer cell line, MIA PaCa-2. Biochem Biophys Res Commun. 2000 Mar 24; 269(3):704-8.
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Signal transduction mechanisms in neurotensin-mediated cellular regulation. Surgery. 1998 Aug; 124(2):239-46; discussion 246-7.
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Clonal strains of rat medullary thyroid carcinoma cells that produce neurotensin and calcitonin. Functional and morphologic studies. Lab Invest. 1983 Oct; 49(4):453-9.
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Regulation of neurotensin release by a continuous line of mammalian C-cells: the role of biogenic amines. Endocrinology. 1983 Apr; 112(4):1240-6.
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Characterization of neurotensin production by a line of rat medullary thyroid carcinoma cells. Proc Natl Acad Sci U S A. 1980 Jun; 77(6):3741-5.