Immunoglobulin A, Secretory
"Immunoglobulin A, Secretory" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The principle immunoglobulin in exocrine secretions such as milk, respiratory and intestinal mucin, saliva and tears. The complete molecule (around 400 kD) is composed of two four-chain units of IMMUNOGLOBULIN A, one SECRETORY COMPONENT and one J chain (IMMUNOGLOBULIN J-CHAINS).
| Descriptor ID |
D007071
|
| MeSH Number(s) |
D12.776.124.486.485.114.619.026.030 D12.776.124.790.651.114.619.026.030 D12.776.377.715.548.114.619.026.030
|
| Concept/Terms |
Immunoglobulin A, Secretory- Immunoglobulin A, Secretory
- Secretory IgA
- IgA, Exocrine
- Exocrine IgA
- SIgA
- IgA, Secretory
- Secretory Immunoglobulin A
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin A, Secretory".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin A, Secretory".
This graph shows the total number of publications written about "Immunoglobulin A, Secretory" by people in this website by year, and whether "Immunoglobulin A, Secretory" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin A, Secretory" by people in Profiles.
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Breast milk delivery of an engineered dimeric IgA protects neonates against rotavirus. Mucosal Immunol. 2025 Apr; 18(2):441-452.
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The impact of the Th17:Treg axis on the IgA-Biome across the glycemic spectrum. PLoS One. 2021; 16(10):e0258812.
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Effect of high-fidelity simulation on alpha-amylase activity and concentrations of secretory immunoglobulin class A, cortisol, and testosterone among medical students. Endocrine. 2021 08; 73(2):431-438.
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Impact of Diabetes on the Gut and Salivary IgA Microbiomes. Infect Immun. 2020 11 16; 88(12).
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Characterization of gp120 hydrolysis by IgA antibodies from humans without HIV infection. AIDS Res Hum Retroviruses. 2007 Dec; 23(12):1541-54.
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Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults. Infect Immun. 2001 Feb; 69(2):988-95.
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Functional analysis of IgA antibodies specific for a conserved epitope within the M protein of group A streptococci from Australian Aboriginal endemic communities. Int Immunol. 1999 Apr; 11(4):569-76.
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Host responses to respiratory virus infection and immunization. Curr Top Microbiol Immunol. 1999; 236:191-214.
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Intranasal monoclonal IgA antibody to respiratory syncytial virus protects rhesus monkeys against upper and lower respiratory tract infection. J Infect Dis. 1996 Aug; 174(2):256-61.
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Antigenicity of amino-acid sequences from Clostridium difficile toxin B. J Med Microbiol. 1996 Jun; 44(6):464-74.