"Multigene Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D005810
|
| MeSH Number(s) |
G05.360.340.024.340.645
|
| Concept/Terms |
Multigene Family- Multigene Family
- Families, Multigene
- Family, Multigene
- Multigene Families
Gene Clusters- Gene Clusters
- Cluster, Gene
- Clusters, Gene
- Gene Cluster
|
Below are MeSH descriptors whose meaning is more general than "Multigene Family".
Below are MeSH descriptors whose meaning is more specific than "Multigene Family".
This graph shows the total number of publications written about "Multigene Family" by people in this website by year, and whether "Multigene Family" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 4 | 7 | 11 |
| 1995 | 8 | 4 | 12 |
| 1996 | 6 | 4 | 10 |
| 1997 | 4 | 10 | 14 |
| 1998 | 4 | 7 | 11 |
| 1999 | 2 | 3 | 5 |
| 2000 | 4 | 3 | 7 |
| 2001 | 4 | 7 | 11 |
| 2002 | 7 | 8 | 15 |
| 2003 | 1 | 8 | 9 |
| 2004 | 1 | 7 | 8 |
| 2005 | 3 | 5 | 8 |
| 2006 | 4 | 5 | 9 |
| 2007 | 3 | 17 | 20 |
| 2008 | 5 | 4 | 9 |
| 2009 | 0 | 7 | 7 |
| 2010 | 2 | 5 | 7 |
| 2011 | 3 | 6 | 9 |
| 2012 | 3 | 1 | 4 |
| 2013 | 2 | 5 | 7 |
| 2014 | 0 | 5 | 5 |
| 2015 | 3 | 8 | 11 |
| 2016 | 2 | 5 | 7 |
| 2017 | 4 | 5 | 9 |
| 2018 | 3 | 7 | 10 |
| 2019 | 1 | 3 | 4 |
| 2020 | 0 | 7 | 7 |
| 2021 | 1 | 9 | 10 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 2 | 2 | 4 |
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Below are the most recent publications written about "Multigene Family" by people in Profiles.
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Large-scale CRISPR/Cas9 deletions within the WFDC gene cluster uncover gene functionality and critical roles in mammalian reproduction. Proc Natl Acad Sci U S A. 2024 Dec 17; 121(51):e2413195121.
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The DLEU2/miR-15a/miR-16-1 cluster shapes the immune microenvironment of chronic lymphocytic leukemia. Blood Cancer J. 2024 10 23; 14(1):168.
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Genome-wide identification and expression analysis of the universal stress protein (USP) gene family in Arabidopsis thaliana, Zea mays, and Oryza sativa. Genetica. 2024 Jun; 152(2-3):119-132.
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The physical and evolutionary energy landscapes of devolved protein sequences corresponding to pseudogenes. Proc Natl Acad Sci U S A. 2024 May 21; 121(21):e2322428121.
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Functional and evolutionary significance of unknown genes from uncultivated taxa. Nature. 2024 Feb; 626(7998):377-384.
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The complete sequence of a human Y chromosome. Nature. 2023 Sep; 621(7978):344-354.
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The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina. Acta Crystallogr F Struct Biol Commun. 2022 Jan 01; 78(Pt 1):1-7.
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Local versus systemic control of bone and skeletal muscle mass by components of the transforming growth factor-? signaling pathway. Proc Natl Acad Sci U S A. 2021 08 17; 118(33).
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An E. coli-Based Biosynthetic Platform Expands the Structural Diversity of Natural Benzoxazoles. ACS Synth Biol. 2021 09 17; 10(9):2151-2158.
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Memory and na?ve gamma delta regulatory T-cell gene expression in the first 24-weeks of peanut oral immunotherapy. Clin Immunol. 2021 09; 230:108820.