"Genes, Essential" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Those genes found in an organism which are necessary for its viability and normal function.
| Descriptor ID |
D020043
|
| MeSH Number(s) |
G05.360.340.024.340.270
|
| Concept/Terms |
Genes, Housekeeping- Genes, Housekeeping
- Gene, Housekeeping
- Housekeeping Gene
- Housekeeping Genes
- Genes, House-keeping
- Gene, House-keeping
- Genes, House keeping
- House-keeping Gene
- House-keeping Genes
|
Below are MeSH descriptors whose meaning is more general than "Genes, Essential".
Below are MeSH descriptors whose meaning is more specific than "Genes, Essential".
This graph shows the total number of publications written about "Genes, Essential" by people in this website by year, and whether "Genes, Essential" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2009 | 1 | 3 | 4 |
| 2012 | 2 | 2 | 4 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, Essential" by people in Profiles.
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A 'Goldmine' for digging cancer-specific targets: the genes essential for embryo development but non-essential for adult life. J Mol Cell Biol. 2020 09 01; 12(9):669-673.
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Promoter-Proximal Chromatin Domain Insulator Protein BEAF Mediates Local and Long-Range Communication with a Transcription Factor and Directly Activates a Housekeeping Promoter in Drosophila. Genetics. 2020 05; 215(1):89-101.
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Human and mouse essentiality screens as a resource for disease gene discovery. Nat Commun. 2020 01 31; 11(1):655.
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Small-molecule targeting of brachyury transcription factor addiction in chordoma. Nat Med. 2019 02; 25(2):292-300.
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Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart. Cardiovasc Res. 2018 02 01; 114(2):247-258.
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Gene Disrupting Mutations Associated with Regression in Autism Spectrum Disorder. J Autism Dev Disord. 2017 Nov; 47(11):3600-3607.
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Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens. G3 (Bethesda). 2017 Aug 07; 7(8):2719-2727.
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Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer. Nature. 2017 02 23; 542(7642):484-488.
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High-throughput discovery of novel developmental phenotypes. Nature. 2016 09 22; 537(7621):508-514.
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Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA. Mol Microbiol. 2016 Mar; 99(5):925-44.