"Genes, Essential" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Those genes found in an organism which are necessary for its viability and normal function.
| Descriptor ID |
D020043
|
| MeSH Number(s) |
G05.360.340.024.340.270
|
| Concept/Terms |
Genes, Housekeeping- Genes, Housekeeping
- Gene, Housekeeping
- Housekeeping Gene
- Housekeeping Genes
- Genes, House-keeping
- Gene, House-keeping
- Genes, House keeping
- House-keeping Gene
- House-keeping Genes
|
Below are MeSH descriptors whose meaning is more general than "Genes, Essential".
Below are MeSH descriptors whose meaning is more specific than "Genes, Essential".
This graph shows the total number of publications written about "Genes, Essential" by people in this website by year, and whether "Genes, Essential" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 2 | 3 |
| 2012 | 1 | 2 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2020 | 1 | 2 | 3 |
| 2024 | 1 | 2 | 3 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, Essential" by people in Profiles.
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In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene. Sci Transl Med. 2025 02 12; 17(785):eadk3920.
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Large-scale identification of chemically induced mutations in Drosophila melanogaster. Genome Res. 2014 Oct; 24(10):1707-18.
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Investigation of the essentiality of glutamate racemase in Mycobacterium smegmatis. J Bacteriol. 2014 Dec; 196(24):4239-44.
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Streptococcus mitis strains causing severe clinical disease in cancer patients. Emerg Infect Dis. 2014 May; 20(5):762-71.
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Passenger deletions generate therapeutic vulnerabilities in cancer. Nature. 2012 Aug 16; 488(7411):337-42.
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Purinergic signaling in human pluripotent stem cells is regulated by the housekeeping gene encoding hypoxanthine guanine phosphoribosyltransferase. Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9):3377-82.
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Functional compensation by duplicated genes in mouse. Trends Genet. 2009 Oct; 25(10):441-2.
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Gene essentiality, gene duplicability and protein connectivity in human and mouse. Trends Genet. 2007 Aug; 23(8):375-8.
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The G23 and G25 genes of temperate mycobacteriophage L1 are essential for the transcription of its late genes. J Biochem Mol Biol. 2007 Mar 31; 40(2):156-62.
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The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev. 2002 Jan 15; 16(2):183-97.