"Genes, Essential" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Those genes found in an organism which are necessary for its viability and normal function.
| Descriptor ID |
D020043
|
| MeSH Number(s) |
G05.360.340.024.340.270
|
| Concept/Terms |
Genes, Housekeeping- Genes, Housekeeping
- Gene, Housekeeping
- Housekeeping Gene
- Housekeeping Genes
- Genes, House-keeping
- Gene, House-keeping
- Genes, House keeping
- House-keeping Gene
- House-keeping Genes
|
Below are MeSH descriptors whose meaning is more general than "Genes, Essential".
Below are MeSH descriptors whose meaning is more specific than "Genes, Essential".
This graph shows the total number of publications written about "Genes, Essential" by people in this website by year, and whether "Genes, Essential" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 2 | 3 |
| 2012 | 1 | 2 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 2 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 2 | 3 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, Essential" by people in Profiles.
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In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene. Sci Transl Med. 2025 Feb 12; 17(785):eadk3920.
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Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines. Sci Rep. 2024 09 30; 14(1):22626.
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An essential gene signature of breast cancer metastasis reveals targetable pathways. Breast Cancer Res. 2024 06 12; 26(1):98.
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Lethal phenotypes in Mendelian disorders. Genet Med. 2024 Jul; 26(7):101141.
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Engineered gut symbiont inhibits microsporidian parasite and improves honey bee survival. Proc Natl Acad Sci U S A. 2023 06 20; 120(25):e2220922120.
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Identification of Essential Genes and Fluconazole Susceptibility Genes in Candida glabrata by Profiling Hermes Transposon Insertions. G3 (Bethesda). 2020 10 05; 10(10):3859-3870.
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A 'Goldmine' for digging cancer-specific targets: the genes essential for embryo development but non-essential for adult life. J Mol Cell Biol. 2020 09 01; 12(9):669-673.
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Promoter-Proximal Chromatin Domain Insulator Protein BEAF Mediates Local and Long-Range Communication with a Transcription Factor and Directly Activates a Housekeeping Promoter in Drosophila. Genetics. 2020 05; 215(1):89-101.
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Human and mouse essentiality screens as a resource for disease gene discovery. Nat Commun. 2020 01 31; 11(1):655.
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Small-molecule targeting of brachyury transcription factor addiction in chordoma. Nat Med. 2019 02; 25(2):292-300.