MARCO DE GIORGI

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Integrative Physiology
AddressOne Baylor Plaza
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. De Giorgi M, Park SH, Castoreno A, Cao M, Hurley A, Saxena L, Chuecos MA, Walkey CJ, Doerfler AM, Furgurson MN, Ljungberg MC, Patel KR, Hyde S, Chickering T, Lefebvre S, Wassarman K, Miller P, Qin J, Schlegel MK, Zlatev I, Li RG, Kim J, Martin JF, Bissig KD, Jadhav V, Bao G, Lagor WR. In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene. bioRxiv. 2023 Jul 29. PMID: 37546995; PMCID: PMC10402145.
      Citations:    
    2. Wang Y, Hurley A, De Giorgi M, Tanner MR, Hu RC, Pennington MW, Lagor WR, Beeton C. Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver. PLoS One. 2023; 18(4):e0283996. PMID: 37040361; PMCID: PMC10089316.
      Citations:    Fields:    Translation:AnimalsCells
    3. Doerfler AM, Park SH, Assini JM, Youssef A, Saxena L, Yaseen AB, De Giorgi M, Chuecos M, Hurley AE, Li A, Marcovina SM, Bao G, Boffa MB, Koschinsky ML, Lagor WR. LPA disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study. Mol Ther Methods Clin Dev. 2022 Dec 08; 27:337-351. PMID: 36381302; PMCID: PMC9630778.
      Citations: 1     
    4. De Giorgi M, Jarrett KE, de Aguiar Vallim TQ, Lagor WR. In Vivo Gene Editing in Lipid and Atherosclerosis Research. Methods Mol Biol. 2022; 2419:673-713. PMID: 35237996.
      Citations:    Fields:    Translation:Animals
    5. De Giorgi M, Li A, Hurley A, Barzi M, Doerfler AM, Cherayil NA, Smith HE, Brown JD, Lin CY, Bissig KD, Bao G, Lagor WR. Targeting the Apoa1 locus for liver-directed gene therapy. Mol Ther Methods Clin Dev. 2021 Jun 11; 21:656-669. PMID: 34141821; PMCID: PMC8166646.
      Citations: 2     
    6. De Giorgi M, Jarrett KE, Burton JC, Doerfler AM, Hurley A, Li A, Hsu RH, Furgurson M, Patel KR, Han J, Borchers CH, Lagor WR. Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase. J Lipid Res. 2020 Dec; 61(12):1675-1686. PMID: 33109681; PMCID: PMC7707164.
      Citations: 4     Fields:    
    7. Pastore N, Huynh T, Herz NJ, Calcagni' A, Klisch TJ, Brunetti L, Kim KH, De Giorgi M, Hurley A, Carissimo A, Mutarelli M, Aleksieva N, D'Orsi L, Lagor WR, Moore DD, Settembre C, Finegold MJ, Forbes SJ, Ballabio A. TFEB regulates murine liver cell fate during development and regeneration. Nat Commun. 2020 05 18; 11(1):2461. PMID: 32424153; PMCID: PMC7235048.
      Citations: 10     Fields:    Translation:AnimalsCells
    8. Li A, Tanner MR, Lee CM, Hurley AE, De Giorgi M, Jarrett KE, Davis TH, Doerfler AM, Bao G, Beeton C, Lagor WR. AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9. Mol Ther. 2020 Jun 03; 28(6):1432-1441. PMID: 32348718; PMCID: PMC7264438.
      Citations: 49     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    9. Li Z, Votava JA, Zajac GJM, Nguyen JN, Leyva Jaimes FB, Ly SM, Brinkman JA, De Giorgi M, Kaul S, Green CL, St Clair SL, Belisle SL, Rios JM, Nelson DW, Sorci-Thomas MG, Lagor WR, Lamming DW, Eric Yen CL, Parks BW. Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism. Cell Metab. 2020 04 07; 31(4):741-754.e5. PMID: 32197071; PMCID: PMC7184639.
      Citations: 7     Fields:    Translation:HumansAnimals
    10. De Giorgi M, Lagor WR. Gene Delivery in Lipid Research and Therapies. Methodist Debakey Cardiovasc J. 2019 Jan-Mar; 15(1):62-69. PMID: 31049151; PMCID: PMC6489604.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    11. Li A, Lee CM, Hurley AE, Jarrett KE, De Giorgi M, Lu W, Balderrama KS, Doerfler AM, Deshmukh H, Ray A, Bao G, Lagor WR. A Self-Deleting AAV-CRISPR System for In?Vivo Genome Editing. Mol Ther Methods Clin Dev. 2019 Mar 15; 12:111-122. PMID: 30619914; PMCID: PMC6313841.
      Citations: 44     
    12. Jarrett KE, Lee C, De Giorgi M, Hurley A, Gillard BK, Doerfler AM, Li A, Pownall HJ, Bao G, Lagor WR. Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research. Arterioscler Thromb Vasc Biol. 2018 09; 38(9):1997-2006. PMID: 30026278; PMCID: PMC6202188.
      Citations: 37     Fields:    Translation:AnimalsCells
    13. Cerrito MG, De Giorgi M, Pelizzoni D, Bonomo SM, Digiacomo N, Scagliotti A, Bugarin C, Gaipa G, Grassilli E, Lavitrano M, Giovannoni R, Bidoli P, Cazzaniga ME. Metronomic combination of Vinorelbine and 5Fluorouracil is able to inhibit triple-negative breast cancer cells. Results from the proof-of-concept VICTOR-0 study. Oncotarget. 2018 Jun 08; 9(44):27448-27459. PMID: 29937997; PMCID: PMC6007943.
      Citations:    
    14. De Giorgi M, Enjyoji K, Jiang G, Csizmadia E, Mitsuhashi S, Gumina RJ, Smolenski RT, Robson SC. Complete deletion of Cd39 is atheroprotective in apolipoprotein E-deficient mice. J Lipid Res. 2017 07; 58(7):1292-1305. PMID: 28487312; PMCID: PMC5496028.
      Citations: 8     Fields:    Translation:AnimalsCells
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