"Genes, Immediate-Early" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters.
| Descriptor ID |
D017781
|
| MeSH Number(s) |
G05.360.340.024.340.330 G05.360.340.024.340.364.875.345 G05.360.340.358.024.875.345 G05.360.340.358.840.500.345
|
| Concept/Terms |
Genes, Immediate-Early- Genes, Immediate-Early
- Genes, Immediate Early
- Immediate-Early Genes
- Gene, Immediate-Early
- Immediate Early Genes
- Immediate-Early Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, Immediate-Early".
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Genome [G05.360.340]
- Genome Components [G05.360.340.024]
- Genes [G05.360.340.024.340]
- Genes, Immediate-Early [G05.360.340.024.340.330]
- Genes, Microbial [G05.360.340.024.340.364]
- Genes, Viral [G05.360.340.024.340.364.875]
- Genes, Immediate-Early [G05.360.340.024.340.364.875.345]
- Genome, Microbial [G05.360.340.358]
- Genes, Microbial [G05.360.340.358.024]
- Genes, Viral [G05.360.340.358.024.875]
- Genes, Immediate-Early [G05.360.340.358.024.875.345]
- Genome, Viral [G05.360.340.358.840]
- Genes, Viral [G05.360.340.358.840.500]
- Genes, Immediate-Early [G05.360.340.358.840.500.345]
Below are MeSH descriptors whose meaning is more specific than "Genes, Immediate-Early".
This graph shows the total number of publications written about "Genes, Immediate-Early" by people in this website by year, and whether "Genes, Immediate-Early" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Genes, Immediate-Early" by people in Profiles.
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The CD33 short isoform is a gain-of-function variant that enhances A?1-42 phagocytosis in microglia. Mol Neurodegener. 2021 03 25; 16(1):19.
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Activation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein. J Biol Chem. 2012 Feb 17; 287(8):5412-25.
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Immediate early genes of glucocorticoid action on the developing intestine. Am J Physiol Gastrointest Liver Physiol. 2005 May; 288(5):G897-906.
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Making the liver young again. Hepatology. 2003 Dec; 38(6):1349-52.
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Development of T-cell lymphomas in Emu-IEX-1 mice. Oncogene. 2003 Oct 09; 22(44):6845-51.
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Microarray analysis of gene expression during bacteriophage T4 infection. Virology. 2002 Aug 01; 299(2):182-91.
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Defective signaling in a subpopulation of CD4(+) T cells in the absence of Ca(2+)/calmodulin-dependent protein kinase IV. Mol Cell Biol. 2002 Jan; 22(1):23-9.
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Nonobligate role of early or sustained expression of immediate-early gene proteins c-fos, c-jun, and Zif/268 in hippocampal mossy fiber sprouting. J Neurosci. 1998 Nov 15; 18(22):9245-55.
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The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation. EMBO J. 1997 May 01; 16(9):2365-75.
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DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes. J Biol Chem. 1997 Jan 03; 272(1):51-7.