"Genes, MDR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes for MEMBRANE TRANSPORT PROTEINS that confer resistance to toxic compounds. Several superfamilies of these multidrug export proteins are known and found in both prokaryotes and eukaryotes.
| Descriptor ID |
D019450
|
| MeSH Number(s) |
G05.360.340.024.340.361 G05.360.340.024.340.645.500
|
| Concept/Terms |
Genes, MDR- Genes, MDR
- Gene, MDR
- MDR Gene
- Multidrug Efflux Pump Genes
- Multidrug Resistance Gene
- Gene, Multidrug Resistance
- Genes, Multidrug Resistance
- Multidrug Resistance Genes
- Resistance Gene, Multidrug
- Resistance Genes, Multidrug
- MDR Genes
|
Below are MeSH descriptors whose meaning is more general than "Genes, MDR".
Below are MeSH descriptors whose meaning is more specific than "Genes, MDR".
This graph shows the total number of publications written about "Genes, MDR" by people in this website by year, and whether "Genes, MDR" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, MDR" by people in Profiles.
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The prevalence of antiseptic tolerance genes among staphylococci and enterococci in a pediatric population. Infect Control Hosp Epidemiol. 2019 03; 40(3):333-340.
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Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome. Cancer. 2011 Feb 15; 117(4):744-51.
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The frequency of C3435T MDR1 gene polymorphism in Iranian patients with ulcerative colitis. Int J Colorectal Dis. 2007 Sep; 22(9):999-1003.
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Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer. J Clin Oncol. 2006 Aug 10; 24(23):3789-98.
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Multidrug resistance modulators PSC 833 and CsA show differential capacity to induce apoptosis in lymphoid leukemia cell lines independently of their MDR phenotype. Leuk Res. 2003 May; 27(5):413-23.
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Wild type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down-regulating multidrug resistance-1 expression. Cancer. 2001 Sep 15; 92(6):1556-66.
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Flipping over flippases. J Pediatr Gastroenterol Nutr. 2001 Jul; 33(1):102-3.
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Gene therapy for paediatric leukaemia. Expert Opin Biol Ther. 2001 Jul; 1(4):663-74.
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Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide. Br J Haematol. 2001 May; 113(2):339-46.
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Treatment of poor prognosis AML patients using PSC833 (valspodar) plus mitoxantrone, etoposide, and cytarabine (PSC-MEC). Adv Exp Med Biol. 1999; 457:47-56.