"Genes, MDR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes for MEMBRANE TRANSPORT PROTEINS that confer resistance to toxic compounds. Several superfamilies of these multidrug export proteins are known and found in both prokaryotes and eukaryotes.
| Descriptor ID |
D019450
|
| MeSH Number(s) |
G05.360.340.024.340.361 G05.360.340.024.340.645.500
|
| Concept/Terms |
Genes, MDR- Genes, MDR
- Gene, MDR
- MDR Gene
- Multidrug Efflux Pump Genes
- Multidrug Resistance Gene
- Gene, Multidrug Resistance
- Genes, Multidrug Resistance
- Multidrug Resistance Genes
- Resistance Gene, Multidrug
- Resistance Genes, Multidrug
- MDR Genes
|
Below are MeSH descriptors whose meaning is more general than "Genes, MDR".
Below are MeSH descriptors whose meaning is more specific than "Genes, MDR".
This graph shows the total number of publications written about "Genes, MDR" by people in this website by year, and whether "Genes, MDR" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 2 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, MDR" by people in Profiles.
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The prevalence of antiseptic tolerance genes among staphylococci and enterococci in a pediatric population. Infect Control Hosp Epidemiol. 2019 03; 40(3):333-340.
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RNA interference-based therapy and its delivery systems. Cancer Metastasis Rev. 2018 03; 37(1):107-124.
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Multidrug resistance-linked gene signature predicts overall survival of patients with primary ovarian serous carcinoma. Clin Cancer Res. 2012 Jun 01; 18(11):3197-206.
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Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome. Cancer. 2011 Feb 15; 117(4):744-51.
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mRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death. Pediatr Blood Cancer. 2009 Dec; 53(6):996-1004.
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Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal. 2009 Jan; 11(1):99-133.
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The frequency of C3435T MDR1 gene polymorphism in Iranian patients with ulcerative colitis. Int J Colorectal Dis. 2007 Sep; 22(9):999-1003.
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Roles of multidrug resistance genes in breast cancer chemoresistance. Adv Exp Med Biol. 2007; 608:23-30.
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Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer. J Clin Oncol. 2006 Aug 10; 24(23):3789-98.
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Molecular cloning of Chinese hamster 1q31 chromosomal fragile site DNA that is important to mdr1 gene amplification reveals a novel gene whose expression is associated with spermatocyte and adipocyte differentiation. Gene. 2006 May 10; 372:44-52.