"Genes, RAG-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes involved in activating the enzyme VDJ recombinase. RAG-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in maturing lymphocytes.
| Descriptor ID |
D016654
|
| MeSH Number(s) |
G05.360.340.024.340.400
|
| Concept/Terms |
Genes, RAG-1- Genes, RAG-1
- Genes, RAG 1
- Recombination-Activating Genes-1
- Recombination Activating Genes 1
- Recombination-Activating Gene-1
- Recombination Activating Gene 1
- RAG-1 Genes
- Gene, RAG-1
- RAG 1 Genes
- RAG-1 Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, RAG-1".
Below are MeSH descriptors whose meaning is more specific than "Genes, RAG-1".
This graph shows the total number of publications written about "Genes, RAG-1" by people in this website by year, and whether "Genes, RAG-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, RAG-1" by people in Profiles.
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In vivo Treg suppression assays. Methods Mol Biol. 2011; 707:119-56.
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Clinical application of DNA microarrays: molecular diagnosis and HLA matching of an Amish child with severe combined immune deficiency. Clin Immunol. 2008 Jul; 128(1):31-8.
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Ontogeny and regulation of IL-7-expressing thymic epithelial cells. J Immunol. 2005 Jan 01; 174(1):60-7.
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Continued expression of recombination-activating genes and TCR gene recombination in human peripheral T cells. Eur J Immunol. 2002 Oct; 32(10):2792-9.
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Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell. 2002 Jun 28; 109(7):811-21.
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V(D)J recombinase activity in a subset of germinal center B lymphocytes. Science. 1997 Oct 10; 278(5336):301-5.
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Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. Science. 1996 Dec 20; 274(5295):2094-7.