"Receptors, Somatostatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the behavior of cells. Somatostatin is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Activated somatostatin receptors on pituitary cells inhibit the release of growth hormone; those on endocrine and gastrointestinal cells regulate the absorption and utilization of nutrients; and those on neurons mediate somatostatin's role as a neurotransmitter.
| Descriptor ID |
D017481
|
| MeSH Number(s) |
D12.776.543.750.695.850 D12.776.543.750.720.600.760 D12.776.543.750.750.555.760 D12.776.543.750.750.580.720 D12.776.543.750.750.700.800
|
| Concept/Terms |
Receptors, Somatostatin- Receptors, Somatostatin
- Somatostatin Receptors
- SRIH Receptors
- Receptors, Somatotropin Release Inhibiting Hormone
- Receptors, SRIH
- Somatostatin Receptor
- Receptor, Somatostatin
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Somatostatin".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Somatostatin [D12.776.543.750.695.850]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Somatostatin [D12.776.543.750.720.600.760]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Somatostatin [D12.776.543.750.750.555.760]
- Receptors, Pancreatic Hormone [D12.776.543.750.750.580]
- Receptors, Somatostatin [D12.776.543.750.750.580.720]
- Receptors, Pituitary Hormone-Regulating Hormone [D12.776.543.750.750.700]
- Receptors, Somatostatin [D12.776.543.750.750.700.800]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatostatin".
This graph shows the total number of publications written about "Receptors, Somatostatin" by people in this website by year, and whether "Receptors, Somatostatin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 2 | 2 | 4 |
| 2002 | 2 | 0 | 2 |
| 2003 | 3 | 1 | 4 |
| 2004 | 2 | 0 | 2 |
| 2005 | 6 | 0 | 6 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 1 | 1 | 2 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Somatostatin" by people in Profiles.
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Somatostatin Receptor 2 Overexpression in Hepatocellular Carcinoma: Implications for Cancer Biology and Therapeutic Applications. Curr Oncol. 2025 Sep 13; 32(9).
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High-Contrast Detection of Somatostatin Receptor Subtype-2 for Fluorescence-Guided Surgery. Mol Pharm. 2022 11 07; 19(11):4241-4253.
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Plasticity in ligand recognition at somatostatin receptors. Nat Struct Mol Biol. 2022 03; 29(3):210-217.
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Pediatric applications of Dotatate: early diagnostic and therapeutic experience. Pediatr Radiol. 2020 06; 50(7):882-897.
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Specific Targeting of Somatostatin Receptor Subtype-2 for Fluorescence-Guided Surgery. Clin Cancer Res. 2019 07 15; 25(14):4332-4342.
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Peptide Receptor Radionuclide Therapy With 177Lu-Octreotate in Patients With Somatostatin Receptor Expressing Neuroendocrine Tumors: Six Years' Assessment. Clin Nucl Med. 2017 Jun; 42(6):436-443.
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A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Sci Transl Med. 2016 06 01; 8(341):341ra76.
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Development and functional characterization of extrahepatic cholangiocyte lines from normal rats. Dig Liver Dis. 2015 Nov; 47(11):964-72.
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Peptide receptor radionuclide therapy with 177Lu-DOTATATE for patients with somatostatin receptor-expressing neuroendocrine tumors: the first US phase 2 experience. Pancreas. 2014 May; 43(4):518-25.
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Somatostatin receptor type 2-based reporter expression after plasmid-based in vivo gene delivery to non-small cell lung cancer. Mol Imaging. 2013 Oct; 12(7):1-10.