"Receptors, Glucagon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors that bind glucagon with high affinity and trigger intracellular changes which influence the behavior of cells. Activation of glucagon receptors causes a variety of effects; the best understood is the initiation of a complex enzymatic cascade in the liver which ultimately increases the availability of glucose to body organs.
| Descriptor ID |
D018027
|
| MeSH Number(s) |
D12.776.543.750.695.330 D12.776.543.750.750.580.350
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Glucagon".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Glucagon".
This graph shows the total number of publications written about "Receptors, Glucagon" by people in this website by year, and whether "Receptors, Glucagon" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 3 | 0 | 3 |
| 2017 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Glucagon" by people in Profiles.
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Glucagon blockade restores functional ?-cell mass in type 1 diabetic mice and enhances function of human islets. Proc Natl Acad Sci U S A. 2021 03 02; 118(9).
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Glucagon Receptor Antagonist-Stimulated a-Cell Proliferation Is Severely Restricted With Advanced Age. Diabetes. 2019 05; 68(5):963-974.
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Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity. Mol Metab. 2017 11; 6(11):1350-1359.
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Acute effects of the glucagon-like peptide 2 analogue, teduglutide, on intestinal adaptation in short bowel syndrome. J Pediatr Gastroenterol Nutr. 2014 Jun; 58(6):694-702.
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Differences in acute anorectic effects of long-acting GLP-1 receptor agonists in rats. Peptides. 2014 Aug; 58:1-6.
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Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect. J Clin Invest. 2014 Jun; 124(6):2456-63.
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Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metab. 2013 Jul 02; 18(1):86-98.
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Cyclic AMP-mediated pleiotropic effects of glucagon-like peptide-1 receptor activation. Focus on "Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a". Am J Physiol Cell Physiol. 2013 Mar; 304(6):C505-7.
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Phosphodiesterase-3 inhibition augments the myocardial infarct size-limiting effects of exenatide in mice with type 2 diabetes. Am J Physiol Heart Circ Physiol. 2013 Jan 01; 304(1):H131-41.
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Glucagon-like peptide-1 and its cardiovascular effects. Curr Atheroscler Rep. 2012 Oct; 14(5):422-8.