"Receptors, Endothelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind ENDOTHELINS with high affinity and trigger intracellular changes which influence the behavior of cells.
| Descriptor ID |
D017466
|
| MeSH Number(s) |
D12.776.543.750.695.220 D12.776.543.750.750.320
|
| Concept/Terms |
Receptors, Endothelin- Receptors, Endothelin
- Receptors, Endothelins
- Receptors, Endothelium-Derived Vasoconstrictor Factor
- Receptors, Endothelium Derived Vasoconstrictor Factor
- Endothelium Derived Vasoconstrictor Factor Receptors
- Endothelin Receptor
- Receptor, Endothelin
- Endothelin Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Endothelin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Endothelin".
This graph shows the total number of publications written about "Receptors, Endothelin" by people in this website by year, and whether "Receptors, Endothelin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2007 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Endothelin" by people in Profiles.
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Opportunities and challenges of pharmacotherapy for pulmonary arterial hypertension in children. Pediatr Pulmonol. 2021 03; 56(3):593-613.
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Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel. Neuro Oncol. 2016 Apr; 18(4):486-96.
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Increased cerebrovascular sensitivity to endothelin-1 in a rat model of obstructive sleep apnea: a role for endothelin receptor B. J Cereb Blood Flow Metab. 2015 Mar; 35(3):402-11.
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Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer. J Pathol. 2014 Sep; 234(1):108-19.
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DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-?-driven epithelial-mesenchymal transition. Cancer Discov. 2013 Oct; 3(10):1172-89.
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Endothelin receptor antagonists in cancer therapy. Cancer Invest. 2007 Dec; 25(8):785-94.
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The endothelin antagonist BQ123 reduces pulmonary vascular resistance after surgical intervention for congenital heart disease. J Thorac Cardiovasc Surg. 2002 Sep; 124(3):435-41.
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Endothelin-1 as a target for therapeutic intervention in prostate cancer. Invest New Drugs. 2002 May; 20(2):173-82.
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Double heterozygosity for a RET substitution interfering with splicing and an EDNRB missense mutation in Hirschsprung disease. Am J Hum Genet. 1999 Apr; 64(4):1216-21.
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Endothelin-1 production and agonist activities in cultured prostate-derived cells: implications for regulation of endothelin bioactivity and bioavailability in prostatic hyperplasia. Prostate. 1998 Mar 01; 34(4):241-50.