"Receptors, LHRH" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors with a 6-kDa protein on the surfaces of cells that secrete LUTEINIZING HORMONE or FOLLICLE STIMULATING HORMONE, usually in the adenohypophysis. LUTEINIZING HORMONE-RELEASING HORMONE binds to these receptors, is endocytosed with the receptor and, in the cell, triggers the release of LUTEINIZING HORMONE or FOLLICLE STIMULATING HORMONE by the cell. These receptors are also found in rat gonads. INHIBINS prevent the binding of GnRH to its receptors.
Descriptor ID |
D011966
|
MeSH Number(s) |
D12.776.543.750.695.410 D12.776.543.750.720.600.460 D12.776.543.750.750.555.460 D12.776.543.750.750.700.460
|
Concept/Terms |
Receptors, LHRH- Receptors, LHRH
- Receptors, Gonadorelin
- Gonadotropin-Releasing Hormone Receptor
- Gonadotropin Releasing Hormone Receptor
- Hormone Receptor, Gonadotropin-Releasing
- Receptor, Gonadotropin-Releasing Hormone
- Gonadotropin Releasing-Hormone Receptors
- Gonadotropin Releasing Hormone Receptors
- Receptors, LHFSHRH
- LHFSHRH Receptors
- LHRH Receptor
- Receptor, LHRH
- LHRH Receptors
- Luliberin Receptors
- Receptors, Luliberin
- Luteinizing Hormone Releasing Hormone Receptors
- Luteinizing Hormone Releasing-Hormone Receptor
- Luteinizing Hormone Releasing Hormone Receptor
- GnRH Receptor
- Receptor, GnRH
- GnRH Receptors
- Receptors, GnRH
- Gonadoliberin Receptors
- Receptors, Gonadoliberin
- Gonadorelin Receptor
- Receptor, Gonadorelin
- Gonadorelin Receptors
- Follicle Stimulating Hormone-Releasing Hormone Receptors
- Follicle Stimulating Hormone Releasing Hormone Receptors
- Receptors, Gonadotropin Releasing-Hormone
- Receptors, Gonadotropin Releasing Hormone
- Releasing-Hormone Receptors, Gonadotropin
|
Below are MeSH descriptors whose meaning is more general than "Receptors, LHRH".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, LHRH [D12.776.543.750.695.410]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, LHRH [D12.776.543.750.720.600.460]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, LHRH [D12.776.543.750.750.555.460]
- Receptors, Pituitary Hormone-Regulating Hormone [D12.776.543.750.750.700]
- Receptors, LHRH [D12.776.543.750.750.700.460]
Below are MeSH descriptors whose meaning is more specific than "Receptors, LHRH".
This graph shows the total number of publications written about "Receptors, LHRH" by people in this website by year, and whether "Receptors, LHRH" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1997 | 1 | 0 | 1 |
1998 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 1 | 1 | 2 |
2006 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, LHRH" by people in Profiles.
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Chronic Estrus Disrupts Uterine Gland Development and Homeostasis. Endocrinology. 2022 03 01; 163(3).
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A multicenter open-label randomized phase II trial of paclitaxel plus EP-100, a novel LHRH receptor-targeted, membrane-disrupting peptide, versus paclitaxel alone for refractory or recurrent ovarian cancer. Gynecol Oncol. 2021 02; 160(2):418-426.
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Enhanced Immunotherapy with LHRH-R Targeted Lytic Peptide in Ovarian Cancer. Mol Cancer Ther. 2020 11; 19(11):2396-2406.
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Whole Exome Sequencing Revealed a Novel Nonsense Variant in the GNRHR Gene Causing Normosmic Hypogonadotropic Hypogonadism in a Pakistani Family. Horm Res Paediatr. 2019; 91(1):9-16.
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GnRH-R-Targeted Lytic Peptide Sensitizes BRCA Wild-type Ovarian Cancer to PARP Inhibition. Mol Cancer Ther. 2019 05; 18(5):969-979.
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Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats. Am J Physiol Gastrointest Liver Physiol. 2017 Nov 01; 313(5):G410-G418.
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Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms. Am J Pathol. 2015 Apr; 185(4):1061-72.
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Restoration of testis function in hypogonadotropic hypogonadal mice harboring a misfolded GnRHR mutant by pharmacoperone drug therapy. Proc Natl Acad Sci U S A. 2013 Dec 24; 110(52):21030-5.
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Emerging association between androgen deprivation therapy and male meningioma: significant expression of luteinizing hormone-releasing hormone receptor in male meningioma. Prostate Cancer Prostatic Dis. 2013 Dec; 16(4):387-90.
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Intratesticular action of kisspeptin in rhesus monkey (Macaca mulatta). Andrologia. 2014 Aug; 46(6):610-7.