"Receptors, Somatotropin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind GROWTH HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells. Activation of growth hormone receptors regulates amino acid transport through cell membranes, RNA translation to protein, DNA transcription, and protein and amino acid catabolism in many cell types. Many of these effects are mediated indirectly through stimulation of the release of somatomedins.
| Descriptor ID |
D011986
|
| MeSH Number(s) |
D12.776.543.750.750.555.770 D12.776.543.750.750.660.750
|
| Concept/Terms |
Receptors, Somatotropin- Receptors, Somatotropin
- Receptor, Growth Hormone
- Somatotropin Receptors
- Receptors, Growth Hormone
- Somatotropin Receptor
- Growth Hormone Receptor
- Hormone Receptor, Growth
- Growth Hormone Receptors
- Hormone Receptors, Growth
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Somatotropin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatotropin".
This graph shows the total number of publications written about "Receptors, Somatotropin" by people in this website by year, and whether "Receptors, Somatotropin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 1 | 3 |
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Somatotropin" by people in Profiles.
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All-cause mortality in patients with acromegaly treated with pegvisomant: an ACROSTUDY analysis. Eur J Endocrinol. 2020 Mar; 182(3):285-292.
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An epidemiological investigation into the association between biomarkers and growth performance in nursery pigs. BMC Vet Res. 2013 Dec 06; 9:247.
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GH receptor plays a major role in liver regeneration through the control of EGFR and ERK1/2 activation. Endocrinology. 2011 Jul; 152(7):2731-41.
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Inhibition of growth hormone receptor activation by pegvisomant may increase bone density in acromegaly. Horm Metab Res. 2011 Jan; 43(1):55-61.
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Potent, nonsteroidal selective androgen receptor modulators (SARMs) based on 8H-[1,4]oxazino[2,3-f]quinolin-8-ones. Bioorg Med Chem Lett. 2007 Oct 01; 17(19):5442-6.
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The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth. Breast Cancer Res Treat. 2006 Aug; 98(3):315-27.
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[Therapeutic management of acromegaly]. Med Klin (Munich). 2006 Jan 15; 101(1):15-23.
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Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4679-84.
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Functional expression of guinea pig growth hormone receptor and its mutants in mammalian cells. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 May; 35(5):403-8.
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Growth hormone receptor is expressed in human breast cancer. Am J Pathol. 2001 Apr; 158(4):1217-22.