"Receptors, Histamine H2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate ADENYLYL CYCLASES. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5)
| Descriptor ID |
D011970
|
| MeSH Number(s) |
D12.776.543.750.670.450.400 D12.776.543.750.695.355 D12.776.543.750.720.480.400
|
| Concept/Terms |
Receptors, Histamine H2- Receptors, Histamine H2
- Histamine H2 Receptors
- H2 Receptors, Histamine
- H2 Receptors
- Receptors, H2
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Histamine H2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Histamine [D12.776.543.750.670.450]
- Receptors, Histamine H2 [D12.776.543.750.670.450.400]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Histamine H2 [D12.776.543.750.695.355]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Histamine [D12.776.543.750.720.480]
- Receptors, Histamine H2 [D12.776.543.750.720.480.400]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Histamine H2".
This graph shows the total number of publications written about "Receptors, Histamine H2" by people in this website by year, and whether "Receptors, Histamine H2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Histamine H2" by people in Profiles.
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Phagocytosis by macrophages depends on histamine H2 receptor signaling and scavenger receptor 1. Microbiologyopen. 2019 10; 8(10):e908.
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Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis. Am J Physiol Gastrointest Liver Physiol. 2019 01 01; 316(1):G205-G216.
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Gut Microbe-Mediated Suppression of Inflammation-Associated Colon Carcinogenesis by Luminal Histamine Production. Am J Pathol. 2017 Oct; 187(10):2323-2336.
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Diacylglycerol kinase synthesized by commensal Lactobacillus reuteri diminishes protein kinase C phosphorylation and histamine-mediated signaling in the mammalian intestinal epithelium. Mucosal Immunol. 2018 03; 11(2):380-393.
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Histamine H2 Receptor-Mediated Suppression of Intestinal Inflammation by Probiotic Lactobacillus reuteri. mBio. 2015 Dec 15; 6(6):e01358-15.
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Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of PKA and ERK signaling. PLoS One. 2012; 7(2):e31951.
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Cytological transformations associated with parietal cell stimulation: critical steps in the activation cascade. J Cell Sci. 1999 Aug; 112 ( Pt 16):2639-46.
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Inverse agonism and the regulation of receptor number. Trends Pharmacol Sci. 1997 Dec; 18(12):468-74.
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Cloning, RNA expression, and chromosomal location of a mouse histamine H2 receptor gene. Genomics. 1996 Nov 01; 37(3):390-4.
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Molecular cloning of a gene encoding the histamine H2 receptor. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5937.