"Oligonucleotide Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
| Descriptor ID |
D015345
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| MeSH Number(s) |
D13.444.600.601 D27.505.259.750.600.650 D27.720.470.530.600.650
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oligonucleotide Probes".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotide Probes".
This graph shows the total number of publications written about "Oligonucleotide Probes" by people in this website by year, and whether "Oligonucleotide Probes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 6 | 6 |
| 1995 | 0 | 7 | 7 |
| 1996 | 0 | 8 | 8 |
| 1997 | 0 | 2 | 2 |
| 1998 | 1 | 2 | 3 |
| 1999 | 1 | 3 | 4 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 3 | 3 |
| 2004 | 2 | 3 | 5 |
| 2005 | 0 | 5 | 5 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 2 | 3 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oligonucleotide Probes" by people in Profiles.
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Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH. J Vis Exp. 2020 09 20; (163).
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Comparison of sequence-specific oligonucleotide probe vs next generation sequencing for HLA-A, B, C, DRB1, DRB3/B4/B5, DQA1, DQB1, DPA1, and DPB1 typing: Toward single-pass high-resolution HLA typing in support of solid organ and hematopoietic cell transplant programs. HLA. 2019 09; 94(3):296-306.
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Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling. PLoS Genet. 2018 12; 14(12):e1007872.
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Sequence selective capture, release and analysis of DNA using a magnetic microbead-assisted toehold-mediated DNA strand displacement reaction. Analyst. 2014 Jul 21; 139(14):3548-51.
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Assessing phagocytic clearance of cell death in experimental stroke by ligatable fluorescent probes. J Vis Exp. 2014 May 27; (87).
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TRAF3 regulates the effector function of regulatory T cells and humoral immune responses. J Exp Med. 2014 Jan 13; 211(1):137-51.
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Measuring mRNA copy number in individual Escherichia coli cells using single-molecule fluorescent in situ hybridization. Nat Protoc. 2013 Jun; 8(6):1100-13.
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Detection of =1Mb microdeletions and microduplications in a single cell using custom oligonucleotide arrays. Prenat Diagn. 2012 Jan; 32(1):10-20.
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Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models. Gut. 2012 Sep; 61(9):1315-22.
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Titration-free massively parallel pyrosequencing using trace amounts of starting material. Nucleic Acids Res. 2010 Jul; 38(13):e137.