"Receptor, Endothelin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of endothelin receptor found predominantly in the VASCULAR SMOOTH MUSCLE. It has a high affinity for ENDOTHELIN-1 and ENDOTHELIN-2.
| Descriptor ID |
D044022
|
| MeSH Number(s) |
D12.776.543.750.695.220.100 D12.776.543.750.750.320.100
|
| Concept/Terms |
Receptor, Endothelin A- Receptor, Endothelin A
- Endothelin A Receptor
- Endothelin Receptors Type A
- Receptor, Endothelin-1
- Endothelin-1 Receptor
- Receptor, Endothelin 1
- Endothelin A Receptors
- Receptors, Endothelin A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Endothelin A".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Endothelin A".
This graph shows the total number of publications written about "Receptor, Endothelin A" by people in this website by year, and whether "Receptor, Endothelin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 2 | 3 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Endothelin A" by people in Profiles.
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Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes. Cancer Res. 2011 Dec 01; 71(23):7259-69.
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CPU0213, a non-selective ETA/ETB receptor antagonist, improves pulmonary arteriolar remodeling of monocrotaline-induced pulmonary hypertension in rats. Clin Exp Pharmacol Physiol. 2009 Feb; 36(2):169-75.
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The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature. J Cardiovasc Pharmacol. 2008 Jul; 52(1):42-8.
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CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation. Naunyn Schmiedebergs Arch Pharmacol. 2008 Nov; 378(5):541-52.
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Endothelin receptors, localized in sympathetic nerve terminals of the heart, modulate norepinephrine release and reperfusion arrhythmias. Basic Res Cardiol. 2007 Mar; 102(2):154-62.
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Endothelin-A receptor blockade and inhaled nitric oxide in a porcine model of meconium aspiration syndrome. Pediatr Res. 2004 Sep; 56(3):353-8.
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The endothelin antagonist BQ123 reduces pulmonary vascular resistance after surgical intervention for congenital heart disease. J Thorac Cardiovasc Surg. 2002 Sep; 124(3):435-41.
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Local injection of endothelin-1 produces pain-like behavior and excitation of nociceptors in rats. J Neurosci. 2001 Jul 15; 21(14):5358-66.
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Hemodynamic effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients with class III to IV congestive heart failure. Circulation. 2001 Feb 20; 103(7):973-80.
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Endothelin-1 production and agonist activities in cultured prostate-derived cells: implications for regulation of endothelin bioactivity and bioavailability in prostatic hyperplasia. Prostate. 1998 Mar 01; 34(4):241-50.