Header Logo

NA LI

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    R01HL164838     (LI, NA)Dec 20, 2023 - Nov 30, 2027
    NIH
    FKBP5 AND CARDIAC ARRHYTHMOGENESIS
    Role: Principal Investigator
    R01HL163277     (LI, NA)Mar 25, 2022 - Feb 28, 2026
    NIH
    Cardiac fibroblast inflammasome and atrial myopathy
    Role: Principal Investigator
    R01HL147108     (LI, NA ;WEHRENS, XANDER H.T.)Apr 15, 2019 - Feb 29, 2024
    NIH
    Mechanisms underlying atrial fibrillation associated with chronic kidney disease
    Role: Co-Principal Investigator
    R01HL136389     (LI, NA)Sep 1, 2017 - Nov 30, 2026
    NIH
    The Role of Gasdermin-D/Interleukin-1 Nexus in Atrial Arrhythmogenesis
    Role: Principal Investigator
    R56HL131649     (LI, NA)Sep 16, 2016 - Aug 31, 2018
    NIH
    Inflammasome mediated pathogenesis of atrial fibrillation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, Griss J, Hogue GFJ, Li NT, Matthews L, May B, Milacic M, Mohammadi H, Petryszak R, Rothfels K, Shamovsky V, Stephan R, Tiwari K, Weiser J, Wright A, Gillespie M, Wu G, Stein L, Hermjakob H, D'Eustachio P. The Reactome Knowledgebase 2026. Nucleic Acids Res. 2026 Jan 06; 54(D1):D673-D681. PMID: 41251150; PMCID: PMC12807730.
      Citations: 3     Fields:    Translation:Humans
    2. Wu G, Matthews L, Boyer N, Milacic M, Beavers D, Li NT, May B, Rothfels K, Shamovsky V, Stephan R, Gillespie M, Hermjakob H, D'Eustachio P, Stein L. Application of Large Language Models for Annotating Genes into Reactome Pathways. bioRxiv. 2025 Dec 23. PMID: 41497647; PMCID: PMC12767520.
      Citations:    
    3. Mohammadi H, Almodaresi F, Hogue GFJ, Wright A, Orlic-Milacic M, Li NT, Mawani A, Stein L. React-to-Me: A Conversational Interface for Interactive Exploration of the Reactome Pathway Knowledgebase. bioRxiv. 2025 Dec 12. PMID: 41427274; PMCID: PMC12714027.
      Citations:    
    4. Grippin AJ, Marconi C, Copling S, Li N, Braun C, Woody C, Young E, Gupta P, Wang M, Wu A, Jeong SD, Soni D, Weidert F, Xie C, Goldenberg E, Kim A, Zhao C, DeVries A, Castillo P, Lohray R, Rooney MK, Schrank BR, Wang Y, Ma Y, Chang E, Kouzy R, Dyson K, Jafarnia J, Nariman N, Gladish G, New J, Argueta A, Amaya D, Thomas N, Doty A, Chen J, Copling N, Alatrash G, Simon J, Davies AB, Dennis W, Liang R, Lewis J, Wei X, Rinsurongkawong W, Vaporciyan AA, Johns A, D3CODE Team, Lee J, Lee JH, Sun R, Sharma P, Tran H, Zhang J, Gibbons DL, Wargo J, Kim BYS, Heymach JV, Mendez-Gomez HR, Jiang W, Sayour EJ, Lin SH. SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade. Nature. 2025 Nov; 647(8089):488-497. PMID: 41125896; PMCID: PMC12611756.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    5. Cao R, Li NT, Shing CB, Kutulakos Z, Tan CM, McGuigan AP. Reproducible Manufacturing of SPOT as a High-throughput Scaffold-based Culture Platform. J Vis Exp. 2025 Jul 29; (221). PMID: 40824916.
      Citations:    Fields:    Translation:Humans
    6. Lin SH, Subbiah V, Neri S, Cohen EN, Li Z, Lu YJ, Son YL, Lyu Y, Braun C, Gao H, Jayachandran G, Sharma A, Ye R, Fang P, Li N, Karp D, Hong D, Rodon J, Yu H, Peng J, Lloyd GK, Tonra JR, Reuben JM, Huang L, Fu S. Plinabulin following radiation enhances dendritic cell maturation and checkpoint inhibitor retreatment of relapsed/refractory cancers. Med. 2025 Oct 10; 6(10):100752. PMID: 40580957.
      Citations:    Fields:    Translation:HumansCellsCTClinical Trials
    7. Navarro-Garcia JA, Keefe JA, Song J, Li N, Wehrens XHT. Mechanisms underlying atrial fibrillation in chronic kidney disease. J Mol Cell Cardiol. 2025 Aug; 205:37-51. PMID: 40499614; PMCID: PMC12809698.
      Citations: 2     Fields:    Translation:HumansAnimals
    8. Li L, Coarfa C, Yuan Y, Abu-Taha I, Wang X, Song J, Zeng Y, Chen X, Koirala A, Grimm SL, Kamler M, McClendon LK, Tallquist M, Nattel S, Dobrev D, Li N. Fibroblast-Restricted Inflammasome Activation Promotes Atrial Fibrillation and Heart Failure With Diastolic Dysfunction. JACC Basic Transl Sci. 2025 Jul; 10(7):101244. PMID: 40243956; PMCID: PMC12434206.
      Citations: 4     
    9. Yuan Y, Martsch P, Chen X, Martinez E, Li L, Song J, Poppenborg T, Bruns F, Kim JH, Kamler M, Martin JF, Abu-Taha I, Dobrev D, Li N. Atrial cardiomyocyte-restricted cleavage of gasdermin D promotes atrial arrhythmogenesis. Eur Heart J. 2025 Apr 01; 46(13):1250-1262. PMID: 39927987; PMCID: PMC11959185.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    10. Faurschou KL, Clasky AJ, Watchorn J, Tram Su J, Li NT, McGuigan AP, Gu FX. Lateral Assessment of Mucomimetic Hydrogels to Evaluate Correlation between Microscopic and Macroscopic Properties. Macromol Biosci. 2024 Dec; 24(12):e2400146. PMID: 39374341.
      Citations:    Fields:    Translation:Humans
    11. Adeleye AG, Chelu MG, Li N. Reading Tea Leaves: Epigallocatechin-3-Gallate for Targeting Atrial Fibrosis. Cardiovasc Drugs Ther. 2024 Dec; 38(6):1189-1190. PMID: 39249195; PMCID: PMC12416510.
      Citations:    Fields:    
    12. Xu W, Cao Y, Stephens SB, Arredondo MJ, Chen Y, Perez W, Sun L, Yu AC, Kim JJ, Lalani SR, Li N, Horrigan FT, Altamirano F, Wehrens XH, Miyake CY, Zhang L. Folate as a potential treatment for lethal ventricular arrhythmias in TANGO2-deficiency disorder. JCI Insight. 2024 Jun 10; 9(11). PMID: 38855866; PMCID: PMC11382877.
      Citations: 2     Fields:    Translation:HumansCells
    13. Saadatagah S, Naderian M, Uddin M, Dikilitas O, Niroula A, Schuermans A, Selvin E, Hoogeveen RC, Matsushita K, Nambi V, Yu B, Chen LY, Bick AG, Ebert BL, Honigberg MC, Li N, Shah A, Natarajan P, Kullo IJ, Ballantyne CM. Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1. JAMA Cardiol. 2024 Jun 01; 9(6):497-506. PMID: 38598228; PMCID: PMC11007653.
      Citations: 19     Fields:    Translation:Humans
    14. Li T, Marashly Q, Kim JA, Li N, Chelu MG. Cardiac conduction diseases: understanding the molecular mechanisms to uncover targets for future treatments. Expert Opin Ther Targets. 2024 May; 28(5):385-400. PMID: 38700451; PMCID: PMC11395937.
      Citations: 2     Fields:    Translation:HumansAnimals
    15. Li N, Chelu MG, Birnbaum Y. Dapagliflozin for Atrial Fibrillation. Cardiovasc Drugs Ther. 2024 Feb; 38(1):1-3. PMID: 38319469; PMCID: PMC11428186.
      Citations: 2     Fields:    Translation:Humans
    16. Scott XO, Li N. How much exercise is too much? Understanding the impact on atrial remodelling. J Physiol. 2024 02; 602(4):535-536. PMID: 38319974; PMCID: PMC11073610.
      Citations:    Fields:    Translation:Humans
    17. Song J, Wu J, Robichaux DJ, Li T, Wang S, Arredondo Sancristobal MJ, Dong B, Dobrev D, Karch J, Thomas SS, Li N. A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome. Cells. 2024 01 05; 13(2). PMID: 38247800; PMCID: PMC10814244.
      Citations: 4     Fields:    Translation:AnimalsCells
    18. Song J, Navarro-Garcia JA, Wu J, Saljic A, Abu-Taha I, Li L, Lahiri SK, Keefe JA, Aguilar-Sanchez Y, Moore OM, Yuan Y, Wang X, Kamler M, Mitch WE, Ruiz-Hurtado G, Hu Z, Thomas SS, Dobrev D, Wehrens XH, Li N. Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation. J Clin Invest. 2023 10 02; 133(19). PMID: 37581942; PMCID: PMC10541185.
      Citations: 29     Fields:    Translation:HumansAnimals
    19. Martinez E, Li N. Blocking interleukin-6 trans-signaling in AF: Promises and challenges. Heart Rhythm. 2023 12; 20(12):1771-1772. PMID: 37696442; PMCID: PMC11441713.
      Citations:    
    20. Yuan Y, Li N. Arriving on time: decoding macrophage involvement in atrial fibrillation. J Cardiovasc Aging. 2023 Nov; 3(4). PMID: 37719782; PMCID: PMC10500608.
      Citations:    
    21. Cao R, Li NT, Latour S, Cadavid JL, Tan CM, Forman A, Jackson HW, McGuigan AP. An Automation Workflow for High-Throughput Manufacturing and Analysis of Scaffold-Supported 3D Tissue Arrays. Adv Healthc Mater. 2023 07; 12(19):e2202422. PMID: 37086259; PMCID: PMC11468893.
      Citations:    
    22. Haensel D, Daniel B, Gaddam S, Pan C, Fabo T, Bjelajac J, Jussila AR, Gonzalez F, Li NY, Chen Y, Hou J, Patel T, Aasi S, Satpathy AT, Oro AE. Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche. Nat Commun. 2023 05 10; 14(1):2685. PMID: 37164949; PMCID: PMC10172319.
      Citations:    
    23. Wang X, Song J, Yuan Y, Li L, Abu-Taha I, Heijman J, Sun L, Dobrev S, Kamler M, Xie L, Wehrens XHT, Horrigan FT, Dobrev D, Li N. Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis. Circ Res. 2023 06 23; 133(1):e1-e16. PMID: 37154033; PMCID: PMC10330339.
      Citations: 13     Fields:    Translation:AnimalsCells
    24. Gawalko M, Saljic A, Li N, Abu-Taha I, Jespersen T, Linz D, Nattel S, Heijman J, Fender A, Dobrev D. Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance. Cardiovasc Res. 2023 05 02; 119(3):614-630. PMID: 35689487; PMCID: PMC10409902.
      Citations: 33     Fields:    Translation:Humans
    25. Zhang L, Li N. Lipid overload - a culprit for hypertrophic cardiomyopathy? J Cardiovasc Aging. 2023 Feb; 3(1). PMID: 36818426; PMCID: PMC9933935.
      Citations:    
    26. Manoj P, Kim JA, Kim S, Li T, Sewani M, Chelu MG, Li N. Sinus node dysfunction: current understanding and future directions. Am J Physiol Heart Circ Physiol. 2023 03 01; 324(3):H259-H278. PMID: 36563014; PMCID: PMC9886352.
      Citations: 21     Fields:    Translation:Humans
    27. Miyake CY, Lay EJ, Soler-Alfonso C, Glinton KE, Houck KM, Tosur M, Moran NE, Stephens SB, Scaglia F, Howard TS, Kim JJ, Pham TD, Valdes SO, Li N, Murali CN, Zhang L, Kava M, Yim D, Beach C, Webster G, Liberman L, Janson CM, Kannankeril PJ, Baxter S, Singer-Berk M, Wood J, Mackenzie SJ, Sacher M, Ghaloul-Gonzalez L, Pedroza C, Morris SA, Ehsan SA, Azamian MS, Lalani SR. Natural history of TANGO2 deficiency disorder: Baseline assessment of 73 patients. Genet Med. 2023 04; 25(4):100352. PMID: 36473599; PMCID: PMC10306319.
      Citations: 16     Fields:    Translation:Humans
    28. Zheng M, Li RG, Song J, Zhao X, Tang L, Erhardt S, Chen W, Nguyen BH, Li X, Li M, Wang J, Evans SM, Christoffels VM, Li N, Wang J. Hippo-Yap Signaling Maintains Sinoatrial Node Homeostasis. Circulation. 2022 11 29; 146(22):1694-1711. PMID: 36317529; PMCID: PMC9897204.
      Citations: 17     Fields:    Translation:HumansAnimals
    29. Li NT, Wu NC, Cao R, Cadavid JL, Latour S, Lu X, Zhu Y, Mijalkovic M, Roozitalab R, Landon-Brace N, Notta F, McGuigan AP. An off-the-shelf multi-well scaffold-supported platform for tumour organoid-based tissues. Biomaterials. 2022 12; 291:121883. PMID: 36343611.
      Citations:    
    30. Ripplinger CM, Glukhov AV, Kay MW, Boukens BJ, Chiamvimonvat N, Delisle BP, Fabritz L, Hund TJ, Knollmann BC, Li N, Murray KT, Poelzing S, Quinn TA, Remme CA, Rentschler SL, Rose RA, Posnack NG. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals. Am J Physiol Heart Circ Physiol. 2022 12 01; 323(6):H1137-H1166. PMID: 36269644; PMCID: PMC9678409.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    31. Ni L, Lahiri SK, Nie J, Pan X, Abu-Taha I, Reynolds JO, Campbell HM, Wang H, Kamler M, Li N, Wei X, Wang DW, Dobrev D, Wehrens XHT, Schmitz W, M?ller FU. Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice. Cardiovasc Res. 2022 10 21; 118(13):2805-2818. PMID: 34648001; PMCID: PMC9586567.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    32. Prodan N, Ershad F, Reyes-Alcaraz A, Li L, Mistretta B, Gonzalez L, Rao Z, Yu C, Gunaratne PH, Li N, Schwartz RJ, McConnell BK. Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells. iScience. 2022 Nov 18; 25(11):105402. PMID: 36388958; PMCID: PMC9646947.
      Citations:    
    33. Dobrev D, Heijman J, Li N, Nattel S, Hiram R. Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology. Nat Rev Cardiol. 2023 03; 20(3):145-167. PMID: 36109633; PMCID: PMC9477170.
      Citations: 134     Fields:    Translation:AnimalsCells
    34. Pieters VM, Rjaibi ST, Singh K, Li NT, Khan ST, Nunes SS, Dal Cin A, Gilbert PM, McGuigan AP. A three-dimensional human adipocyte model of fatty acid-induced obesity. Biofabrication. 2022 08 19; 14(4). PMID: 35896099.
      Citations:    
    35. Li N, Tan M, Thuma PE, Grigorenko EL. Pediatric Symptom Checklist-17: Factor Structure and Uniform Differential Item Functioning Across Gender and Age in HIV Orphans and Vulnerable Children in Zambia. Eur J Psychol Assess. 2023 May; 39(3):165-175. PMID: 37485035; PMCID: PMC10361684.
      Citations: 1     
    36. Miyake CY, Lay EJ, Beach CM, Ceresnak SR, Delauz CM, Howard TS, Janson CM, Jardine K, Kannankeril PJ, Kava M, Kim JJ, Liberman L, Macicek SL, Pham TD, Robertson T, Valdes SO, Webster G, Stephens SB, Milewicz DM, Azamian M, Ehsan SA, Houck KM, Soler-Alfonso C, Glinton KE, Tosur M, Li N, Xu W, Lalani SR, Zhang L. Cardiac crises: Cardiac arrhythmias and cardiomyopathy during TANGO2 deficiency related metabolic crises. Heart Rhythm. 2022 10; 19(10):1673-1681. PMID: 35568137; PMCID: PMC10642301.
      Citations: 14     Fields:    Translation:Humans
    37. Li N, Durgan DJ, Wehrens XHT. Gut microbiota: a key regulator of ageing-associated atrial fibrillation? Cardiovasc Res. 2022 02 21; 118(3):657-659. PMID: 34849621; PMCID: PMC8859633.
      Citations:    Fields:    Translation:Humans
    38. Song J, Li N, Dobrev D. Proteomics: A promising approach to discover new biomarkers for atrial fibrillation. Int J Cardiol. 2021 12 15; 345:125-126. PMID: 34710496; PMCID: PMC8876401.
      Citations:    Fields:    Translation:Humans
    39. Linz D, Gawalko M, Sanders P, Penders J, Li N, Nattel S, Dobrev D. Does gut microbiota affect atrial rhythm? Causalities and speculations. Eur Heart J. 2021 09 14; 42(35):3521-3525. PMID: 34338744; PMCID: PMC8442110.
      Citations: 12     Fields:    Translation:Humans
    40. Scott L, Fender AC, Saljic A, Li L, Chen X, Wang X, Linz D, Lang J, Hohl M, Twomey D, Pham TT, Diaz-Lankenau R, Chelu MG, Kamler M, Entman ML, Taffet GE, Sanders P, Dobrev D, Li N. NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias. Cardiovasc Res. 2021 06 16; 117(7):1746-1759. PMID: 33523143; PMCID: PMC8208743.
      Citations: 94     Fields:    Translation:HumansAnimalsCells
    41. Kim JA, Chelu MG, Li N. Genetics of atrial fibrillation. Curr Opin Cardiol. 2021 05 01; 36(3):281-287. PMID: 33818546; PMCID: PMC8211390.
      Citations: 12     Fields:    
    42. Wang X, Chen X, Dobrev D, Li N. The crosstalk between cardiomyocyte calcium and inflammasome signaling pathways in atrial fibrillation. Pflugers Arch. 2021 03; 473(3):389-405. PMID: 33511453; PMCID: PMC7940593.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    43. Heijman J, Muna AP, Veleva T, Molina CE, Sutanto H, Tekook M, Wang Q, Abu-Taha IH, Gorka M, Kamler M, Ravens U, Li N, Wehrens XHT, Dobrev D, K?nzel S, El-Armouche A, Reichenspurner H, Nikolaev V, Nattel S. Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation. Circ Res. 2020 09 25; 127(8):1036-1055. PMID: 32762493; PMCID: PMC7604886.
      Citations: 163     Fields:    Translation:HumansAnimalsCells
    44. Li N, Brundel BJJM. Inflammasomes and Proteostasis Novel Molecular Mechanisms Associated With Atrial Fibrillation. Circ Res. 2020 06 19; 127(1):73-90. PMID: 32717176; PMCID: PMC7388703.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    45. Li NY, Poh GQ, Teng GCW, Chen HH, Chan DSG, Chan SP, Tambyah PA, Bagdasarian N, Wu JE. A Prediction Tool for the Presence of Ceftriaxone-Resistant Uropathogens upon Hospital Admission. Antibiotics (Basel). 2020 Jun 10; 9(6). PMID: 32531880; PMCID: PMC7345845.
      Citations:    
    46. Fender AC, Kleeschulte S, Stolte S, Leineweber K, Kamler M, Li N, Dobrev D, Bode J. Thrombin receptor PAR4 drives canonical NLRP3 inflammasome signaling in the heart. Basic Res Cardiol. 2020 01 07; 115(2):10. PMID: 31912235; PMCID: PMC7384378.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    47. Scott L, Li N. From Neutrophil Calcium Sensor to Myocardial Remodelling-A Double-Edged Pathway Guided by the Inflammasome. Can J Cardiol. 2020 06; 36(6):813-815. PMID: 32173053; PMCID: PMC7357274.
      Citations:    Fields:    Translation:HumansCells
    48. Zhang M, Hill MC, Kadow ZA, Suh JH, Tucker NR, Hall AW, Tran TT, Swinton PS, Leach JP, Margulies KB, Ellinor PT, Li N, Martin JF. Long-range Pitx2c enhancer-promoter interactions prevent predisposition to atrial fibrillation. Proc Natl Acad Sci U S A. 2019 11 05; 116(45):22692-22698. PMID: 31636200; PMCID: PMC6842642.
      Citations: 40     Fields:    Translation:AnimalsCells
    49. Li NT, Rodenhizer D, Mou J, Shahaj A, Samardzic K, McGuigan AP. Development of a bioprinting approach for automated manufacturing of multi-cell type biocomposite TRACER strips using contact capillary-wicking. Biofabrication. 2019 10 21; 12(1):015001. PMID: 31553953.
      Citations:    
    50. Greer-Short A, Musa H, Alsina KM, Ni L, Word TA, Reynolds JO, Gratz D, Lane C, El-Refaey M, Unudurthi S, Skaf M, Li N, Fedorov VV, Wehrens XHT, Mohler PJ, Hund TJ. Calmodulin kinase II regulates atrial myocyte late sodium current, calcium handling, and atrial arrhythmia. Heart Rhythm. 2020 03; 17(3):503-511. PMID: 31622781; PMCID: PMC7056561.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    51. Suryavanshi SV, Li N. Beh?et's disease: A (silk) route to atrial fibrillation? Int J Cardiol. 2019 10 15; 293:117-118. PMID: 31353152; PMCID: PMC7654502.
      Citations:    Fields:    Translation:Humans
    52. Alsina KM, Hulsurkar M, Kownatzki-Danger D, Abu-Taha I, Kamler M, Chiang DY, Lahiri SK, Reynolds JO, Quick AP, Scott L, Word TA, Gelves MD, Heck AJR, Li N, Dobrev D, Wehrens XHT, Brandenburg S, Lenz C, Urlaub H, Lehnart SE. Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation. Circulation. 2019 08 20; 140(8):681-693. PMID: 31185731; PMCID: PMC6699925.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    53. Ni L, Scott L, Campbell HM, Pan X, Alsina KM, Reynolds J, Philippen LE, Hulsurkar M, Lagor WR, Li N, Wehrens XHT. Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector. Circ Res. 2019 01 18; 124(2):256-262. PMID: 30582449; PMCID: PMC6336523.
      Citations: 18     Fields:    Translation:AnimalsCells
    54. Yao C, Veleva T, Scott L, Cao S, Li L, Chen G, Jeyabal P, Pan X, Alsina KM, Abu-Taha I, Ghezelbash S, Reynolds CL, Shen YH, LeMaire SA, El-Armouche A, Tony Eissa N, Beeton C, Nattel S, Wehrens XHT, Dobrev D, Li N, Schmitz W, M?ller FU. Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation. Circulation. 2018 11 13; 138(20):2227-2242. PMID: 29802206; PMCID: PMC6252285.
      Citations: 136     Fields:    Translation:HumansAnimalsCells
    55. Scott L, Li N, Dobrev D. Role of inflammatory signaling in atrial fibrillation. Int J Cardiol. 2019 07 15; 287:195-200. PMID: 30316645; PMCID: PMC6447485.
      Citations: 26     Fields:    Translation:HumansCells
    56. Pan X, Philippen L, Lahiri SK, Lee C, Park SH, Word TA, Li N, Jarrett KE, Gupta R, Reynolds JO, Lin J, Bao G, Lagor WR, Wehrens XHT. In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia. Circ Res. 2018 Sep 28; 123(8):953-963. PMID: 30355031; PMCID: PMC6206886.
      Citations: 20     Fields:    Translation:AnimalsCells
    57. Chelu MG, Li N. "Sorting" SERCA2a: A novel therapeutic strategy in heart failure? Int J Cardiol. 2018 12 01; 272:306-307. PMID: 30144996; PMCID: PMC6478160.
      Citations:    Fields:    Translation:Humans
    58. Chen G, Chelu MG, Dobrev D, Li N. Cardiomyocyte Inflammasome Signaling in Cardiomyopathies and Atrial Fibrillation: Mechanisms and Potential Therapeutic Implications. Front Physiol. 2018; 9:1115. PMID: 30150941; PMCID: PMC6100656.
      Citations: 21     
    59. Chelu MG, Li N. Biomarkers (plasma trimethylamine-N-oxide) to predict atrial fibrillation: Are we there yet? Int J Cardiol. 2018 09 15; 267:116-117. PMID: 29885821; PMCID: PMC6481160.
      Citations: 2     Fields:    Translation:Humans
    60. Wang Q, Quick AP, Cao S, Reynolds J, Chiang DY, Beavers D, Li N, Wang G, Rodney GG, Anderson ME, Wehrens XHT. Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy. Circ Arrhythm Electrophysiol. 2018 04; 11(4):e005682. PMID: 29654126; PMCID: PMC5903581.
      Citations: 18     Fields:    Translation:AnimalsCells
    61. Lai YC, Li N, Lawrence W, Wang S, Levine A, Burchhardt DM, Pautler RG, Wehrens XH, Anderson AE, Valderr?bano M. Myocardial remodeling and susceptibility to ventricular tachycardia in a model of chronic epilepsy. Epilepsia Open. 2018 Jun; 3(2):213-223. PMID: 29881800; PMCID: PMC5983128.
      Citations: 3     Fields:    
    62. Li N, Dobrev D. Targeting atrial fibrillation promoting atrial structural remodeling: is this a viable strategy in patients with heart failure? Naunyn Schmiedebergs Arch Pharmacol. 2018 03; 391(3):231-233. PMID: 29327256; PMCID: PMC5812790.
      Citations: 1     Fields:    Translation:Humans
    63. Klipp RC, Li N, Wang Q, Word TA, Sibrian-Vazquez M, Strongin RM, Wehrens XHT, Abramson JJ. EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2. Heart Rhythm. 2018 04; 15(4):578-586. PMID: 29248564; PMCID: PMC5879004.
      Citations: 11     Fields:    Translation:AnimalsCells
    64. Li N, Dobrev D. Hyperuricemia: A causal player or a bystander linking inflammatory signaling and atrial fibrillation? Int J Cardiol. 2017 Mar 15; 231:177-178. PMID: 27993379; PMCID: PMC7959481.
      Citations: 3     Fields:    Translation:HumansCells
    65. Li N, Wang Q, Sibrian-Vazquez M, Klipp RC, Reynolds JO, Word TA, Scott L, Salama G, Strongin RM, Abramson JJ, Wehrens XHT. Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs. Int J Cardiol. 2017 Jan 15; 227:668-673. PMID: 27838126; PMCID: PMC5164850.
      Citations: 18     Fields:    Translation:Animals
    66. Uchinoumi H, Yang Y, Oda T, Li N, Alsina KM, Puglisi JL, Chen-Izu Y, Cornea RL, Wehrens XHT, Bers DM. CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift. J Mol Cell Cardiol. 2016 09; 98:62-72. PMID: 27318036; PMCID: PMC5026590.
      Citations: 34     Fields:    Translation:AnimalsCells
    67. Li N, Wehrens XH, Schulte JS, Fehrmann E, Tekook MA, Kranick D, Fels B, Heinick A, Seidl MD, Schmitz W, M?ller FU. Cardiac expression of the CREM repressor isoform CREM-Ib?C-X in mice leads to arrhythmogenic alterations in ventricular cardiomyocytes. Basic Res Cardiol. 2016 Mar; 111(2):15. PMID: 26818679; PMCID: PMC4729809.
      Citations: 7     Fields:    Translation:AnimalsCells
    68. Li N, Dobrev D, Wehrens XH. PITX2: a master regulator of cardiac channelopathy in atrial fibrillation? Cardiovasc Res. 2016 Mar 01; 109(3):345-7. PMID: 26782118; PMCID: PMC4752046.
      Citations: 5     Fields:    Translation:Humans
    69. Li N. Editorial Commentary: The emerging role of epigenetics in atrial fibrillation. Trends Cardiovasc Med. 2016 May; 26(4):319-20. PMID: 26521064.
      Citations: 1     Fields:    Translation:Humans
    70. Glasscock E, Voigt N, McCauley MD, Sun Q, Li N, Chiang DY, Zhou XB, Molina CE, Thomas D, Schmidt C, Skapura DG, Noebels JL, Dobrev D, Wehrens XH. Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation. Basic Res Cardiol. 2015 Sep; 110(5):505. PMID: 26162324; PMCID: PMC5109931.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    71. Xie L, Pi X, Townley-Tilson WH, Li N, Wehrens XH, Entman ML, Taffet GE, Mishra A, Peng J, Schisler JC, Meissner G, Patterson C. PHD2/3-dependent hydroxylation tunes cardiac response to ?-adrenergic stress via phospholamban. J Clin Invest. 2015 Jul 01; 125(7):2759-71. PMID: 26075818; PMCID: PMC4563684.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    72. Chiang DY, Zhang M, Voigt N, Alsina KM, Jakob H, Martin JF, Dobrev D, Wehrens XHT, Li N. Identification of microRNA-mRNA dysregulations in paroxysmal atrial fibrillation. Int J Cardiol. 2015 Apr 01; 184:190-197. PMID: 25706326; PMCID: PMC4417399.
      Citations: 22     Fields:    Translation:Humans
    73. Chiang DY, Kongchan N, Beavers DL, Alsina KM, Voigt N, Neilson JR, Jakob H, Martin JF, Dobrev D, Wehrens XH, Li N. Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release. Circ Arrhythm Electrophysiol. 2014 Dec; 7(6):1214-22. PMID: 25389315; PMCID: PMC4270890.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    74. Wang J, Bai Y, Li N, Ye W, Zhang M, Greene SB, Tao Y, Chen Y, Wehrens XH, Martin JF. Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):9181-6. PMID: 24927531; PMCID: PMC4078868.
      Citations: 53     Fields:    Translation:HumansAnimals
    75. Chiang DY, Li N, Wang Q, Alsina KM, Quick AP, Reynolds JO, Wang G, Skapura D, Voigt N, Dobrev D, Wehrens XH. Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation. Cardiovasc Res. 2014 Jul 01; 103(1):178-87. PMID: 24812280; PMCID: PMC4133595.
      Citations: 33     Fields:    Translation:AnimalsCells
    76. Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, Respress JL, Ather S, Skapura DG, Jordan VK, Horrigan FT, Valderrabano M, Dobrev D, Wehrens XHT, Schmitz W, M?ller FU, Nattel S. Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model. Circulation. 2014 Mar 25; 129(12):1276-1285. PMID: 24398018; PMCID: PMC4026172.
      Citations: 83     Fields:    Translation:AnimalsCells
    77. Chiang DY, Cuthbertson DW, Ruiz FR, Li N, Pereira FA. A coregulatory network of NR2F1 and microRNA-140. PLoS One. 2013; 8(12):e83358. PMID: 24349493; PMCID: PMC3857795.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    78. Voigt N, Heijman J, Wang Q, Chiang DY, Li N, Karck M, Wehrens XHT, Dobrev D, Nattel S. Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation. Circulation. 2014 Jan 14; 129(2):145-156. PMID: 24249718; PMCID: PMC4342412.
      Citations: 174     Fields:    Translation:HumansCells
    79. Purohit A, Rokita AG, Guan X, Chen B, Koval OM, Voigt N, Neef S, Sowa T, Gao Z, Luczak ED, Stefansdottir H, Behunin AC, Li N, El-Accaoui RN, Yang B, Swaminathan PD, Weiss RM, Wehrens XH, Song LS, Dobrev D, Maier LS, Anderson ME. Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation. 2013 Oct 15; 128(16):1748-57. PMID: 24030498; PMCID: PMC3876034.
      Citations: 128     Fields:    Translation:HumansAnimalsCells
    80. Beavers DL, Wang W, Ather S, Voigt N, Garbino A, Dixit SS, Landstrom AP, Li N, Wang Q, Olivotto I, Dobrev D, Ackerman MJ, Wehrens XHT. Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization. J Am Coll Cardiol. 2013 Nov 19; 62(21):2010-9. PMID: 23973696; PMCID: PMC3830688.
      Citations: 86     Fields:    Translation:AnimalsCells
    81. Ather S, Respress JL, Li N, Wehrens XH. Alterations in ryanodine receptors and related proteins in heart failure. Biochim Biophys Acta. 2013 Dec; 1832(12):2425-31. PMID: 23770282; PMCID: PMC3800473.
      Citations: 25     Fields:    Translation:HumansAnimals
    82. Wehrens XH, Chiang DY, Li N. Chronic exercise: a contributing factor to atrial fibrillation? J Am Coll Cardiol. 2013 Jul 02; 62(1):78-80. PMID: 23583764; PMCID: PMC3702168.
      Citations: 1     Fields:    Translation:Animals
    83. Cheng H, Lao DH, Na L, van Oort RJ, Brown JH, Wehrens XH, Chen J, Bers DM, Pereira L. Epac2 mediates cardiac ?1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia. Circulation. 2013 Feb 26; 127(8):913-22. PMID: 23363625; PMCID: PMC3690126.
      Citations: 76     Fields:    Translation:AnimalsCells
    84. Ather S, Wang W, Wang Q, Li N, Anderson ME, Wehrens XH. Inhibition of CaMKII phosphorylation of RyR2 prevents inducible ventricular arrhythmias in mice with Duchenne muscular dystrophy. Heart Rhythm. 2013 Apr; 10(4):592-9. PMID: 23246599; PMCID: PMC3605194.
      Citations: 30     Fields:    Translation:AnimalsCells
    85. Li N, Wehrens XH. Extinguishing intracellular calcium leak: a promising antiarrhythmic approach. Heart Rhythm. 2013 Jan; 10(1):108-9. PMID: 23085093; PMCID: PMC4327983.
      Citations: 1     Fields:    Translation:Animals
    86. DeGrande S, Nixon D, Koval O, Curran JW, Wright P, Wang Q, Kashef F, Chiang D, Li N, Wehrens XH, Anderson ME, Hund TJ, Mohler PJ. CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome. Heart Rhythm. 2012 Dec; 9(12):2034-41. PMID: 23059182; PMCID: PMC3630478.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    87. Respress JL, van Oort RJ, Li N, Rolim N, Dixit SS, deAlmeida A, Voigt N, Lawrence WS, Skapura DG, Wieland T, Ai X, Pogwizd SM, Dobrev D, Wehrens XH, Sk?rdal K, Wisl?ff U. Role of RyR2 phosphorylation at S2814 during heart failure progression. Circ Res. 2012 May 25; 110(11):1474-83. PMID: 22511749; PMCID: PMC3371642.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    88. Voigt N, Li N, Wang Q, Wang W, Trafford AW, Abu-Taha I, Sun Q, Wieland T, Ravens U, Nattel S, Wehrens XH, Dobrev D. Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation. Circulation. 2012 May 01; 125(17):2059-70. PMID: 22456474; PMCID: PMC4663993.
      Citations: 243     Fields:    Translation:HumansAnimalsCells
    89. Li N, Wang T, Wang W, Cutler MJ, Wang Q, Voigt N, Rosenbaum DS, Dobrev D, Wehrens XH. Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice. Circ Res. 2012 Feb 03; 110(3):465-70. PMID: 22158709; PMCID: PMC3272138.
      Citations: 65     Fields:    Translation:AnimalsCells
    90. Marijon E, Fabritz L, Li N, Wang W, Wang T, Schulte K, Hanstein J, Schulte JS, Vogel M, Mougenot N, Laakmann S, Fortmueller L, Eckstein J, Verheule S, Kaese S, Staab A, Grote-Wessels S, Schotten U, Moubarak G, Wehrens XH, Schmitz W, Kirchhof P, Hatem S, M?ller FU. Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice. Int J Cardiol. 2013 Jun 20; 166(2):366-74. PMID: 22093963; PMCID: PMC7647839.
      Citations: 27     Fields:    Translation:Animals
    91. Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, Koval O, Li J, Gudmundsson H, Gumina RJ, Karck M, Schott JJ, Probst V, Le Marec H, Anderson ME, Dobrev D, Wehrens XH, Mohler PJ. Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation. Circulation. 2011 Sep 13; 124(11):1212-22. PMID: 21859974; PMCID: PMC3211046.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    92. Sarma S, Li N, van Oort RJ, Reynolds C, Skapura DG, Wehrens XH. Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):13165-70. PMID: 20615971; PMCID: PMC2919918.
      Citations: 35     Fields:    Translation:AnimalsCells
    93. Li N, Wehrens XH. Programmed electrical stimulation in mice. J Vis Exp. 2010 May 26; (39). PMID: 20512106; PMCID: PMC3152855.
      Citations: 23     Fields:    Translation:Animals
    94. Li N, Jia N, Dai DZ, Hu C, Dai Y. Role of endothelin in the effects of isoprenaline on potassium currents and calsequestrin 2 expression in the heart. Clin Exp Pharmacol Physiol. 2010 May; 37(5-6):557-63. PMID: 20529095.
      Citations: 2     Fields:    Translation:AnimalsCells
    95. van Oort RJ, Respress JL, Li N, Reynolds C, De Almeida AC, Skapura DG, De Windt LJ, Wehrens XH. Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model. Hypertension. 2010 Apr; 55(4):932-8. PMID: 20157052; PMCID: PMC2843393.
      Citations: 31     Fields:    Translation:AnimalsCells
    96. Qi MY, Feng Y, Dai DZ, Li N, Cheng YS, Dai Y. CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity. Acta Pharmacol Sin. 2010 Feb; 31(2):165-74. PMID: 20139899; PMCID: PMC4002834.
      Citations: 14     Fields:    Translation:AnimalsCells
    97. Mathur N, Sood S, Wang S, van Oort RJ, Sarma S, Li N, Skapura DG, Bayle JH, Wehrens XH, Valderr?bano M. Sudden infant death syndrome in mice with an inherited mutation in RyR2. Circ Arrhythm Electrophysiol. 2009 Dec; 2(6):677-85. PMID: 20009080; PMCID: PMC2796595.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    98. Chelu MG, Sarma S, Sood S, Wang S, van Oort RJ, Skapura DG, Li N, Santonastasi M, Schmitz W, Schotten U, Anderson ME, Dobrev D, Wehrens XH, M?ller FU, Valderr?bano M. Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice. J Clin Invest. 2009 Jul; 119(7):1940-51. PMID: 19603549; PMCID: PMC2701862.
      Citations: 213     Fields:    Translation:HumansAnimalsCells
    99. Qi MY, Liu HR, Dai DZ, Li N, Dai Y. Total triterpene acids, active ingredients from Fructus Corni, attenuate diabetic cardiomyopathy by normalizing ET pathway and expression of FKBP12.6 and SERCA2a in streptozotocin-rats. J Pharm Pharmacol. 2008 Dec; 60(12):1687-94. PMID: 19000375.
      Citations: 12     Fields:    Translation:AnimalsCells
    100. Cui B, Cheng YS, Dai DZ, Li N, Zhang TT, Dai Y. CPU0213, a non-selective ETA/ETB receptor antagonist, improves pulmonary arteriolar remodeling of monocrotaline-induced pulmonary hypertension in rats. Clin Exp Pharmacol Physiol. 2009 Feb; 36(2):169-75. PMID: 18986320.
      Citations: 9     Fields:    Translation:Animals
    101. Xu J, Li N, Dai DZ, Yu F, Dai Y. The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature. J Cardiovasc Pharmacol. 2008 Jul; 52(1):42-8. PMID: 18594475.
      Citations: 7     Fields:    Translation:AnimalsCells
    102. Li N, Jia N, Dai DZ, Dai Y. Endothelin receptor antagonist CPU0213 and vitamin E reverse downregulation of FKBP12.6 and SERCA2a: a role of hyperphosphorylation of PKCepsilon. Eur J Pharmacol. 2008 Sep 04; 591(1-3):211-8. PMID: 18611397.
      Citations: 8     Fields:    Translation:AnimalsCells
    103. Li N, Dai DZ, Dai Y. CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation. Naunyn Schmiedebergs Arch Pharmacol. 2008 Nov; 378(5):541-52. PMID: 18548232.
      Citations: 11     Fields:    Translation:AnimalsCells
    104. Li N, Yang L, Dai DZ, Wang QJ, Dai Y. Chiral separation of racemate CPU86017, an anti-arrhythmic agent, produces stereoisomers possessing favourable ion channel blockade and less alpha-adrenoceptor antagonism. Clin Exp Pharmacol Physiol. 2008 May; 35(5-6):643-50. PMID: 18177475.
      Citations: 5     Fields:    Translation:AnimalsCells
    105. Huang ZJ, Dai DZ, Li N, Na T, Ji M, Dai Y. Calcium antagonist property of CPU228, a dofetilide derivative, contributes to its low incidence of torsades de pointes in rabbits. Clin Exp Pharmacol Physiol. 2007 Apr; 34(4):310-7. PMID: 17324143.
      Citations: 3     Fields:    Translation:AnimalsCells
    LI's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (411)
    Explore
    _
    Co-Authors (51)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _