Low Density Lipoprotein Receptor-Related Protein-6
"Low Density Lipoprotein Receptor-Related Protein-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An LDL-receptor related protein that combines with cell surface FRIZZLED RECEPTORS to form WNT PROTEIN-binding receptors. The protein plays an important role in the WNT SIGNALING PATHWAY during EMBRYONIC DEVELOPMENT and in regulation of vascular cell proliferation.
| Descriptor ID |
D060488
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| MeSH Number(s) |
D12.776.526.600 D12.776.543.750.710.450.500.600 D12.776.543.750.850.781
|
| Concept/Terms |
Low Density Lipoprotein Receptor-Related Protein-6- Low Density Lipoprotein Receptor-Related Protein-6
- Low Density Lipoprotein Receptor Related Protein 6
- Low Density Lipoprotein Receptor-Related Protein 6
- Lipoprotein Receptor-Related Protein 6
- Lipoprotein Receptor Related Protein 6
|
Below are MeSH descriptors whose meaning is more general than "Low Density Lipoprotein Receptor-Related Protein-6".
Below are MeSH descriptors whose meaning is more specific than "Low Density Lipoprotein Receptor-Related Protein-6".
This graph shows the total number of publications written about "Low Density Lipoprotein Receptor-Related Protein-6" by people in this website by year, and whether "Low Density Lipoprotein Receptor-Related Protein-6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Low Density Lipoprotein Receptor-Related Protein-6" by people in Profiles.
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Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis. J Dent Res. 2018 Jan; 97(1):49-59.
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Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6. Gastroenterology. 2017 05; 152(6):1477-1491.
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Novel mutations in LRP6 highlight the role of WNT signaling in tooth agenesis. Genet Med. 2016 11; 18(11):1158-1162.
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Rare LRP6 variants identified in spina bifida patients. Hum Mutat. 2015 Mar; 36(3):342-9.
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Polarization of the vacuolar adenosine triphosphatase delineates a transition to high-grade pancreatic intraepithelial neoplasm lesions. Pancreas. 2014 Nov; 43(8):1256-63.
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Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects. Birth Defects Res A Clin Mol Teratol. 2014 Aug; 100(8):623-32.
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Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma. Clin Cancer Res. 2013 Nov 15; 19(22):6242-51.
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Caveolin-1-LRP6 signaling module stimulates aerobic glycolysis in prostate cancer. Cancer Res. 2013 Mar 15; 73(6):1900-11.
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Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/?-catenin signaling. J Cell Biol. 2011 Sep 05; 194(5):737-50.
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Wnt and mammary stem cells: hormones cannot fly wingless. Curr Opin Pharmacol. 2010 Dec; 10(6):643-9.