Bone Morphogenetic Protein 15
"Bone Morphogenetic Protein 15" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein that plays a role in GRANULOSA CELLS where it regulates folliculogenesis. Mutations in the gene for bone morphogenetic protein 15 are linked to reproductive abnormalities such as PREMATURE OVARIAN FAILURE.
| Descriptor ID |
D055430
|
| MeSH Number(s) |
D12.644.276.954.200.900 D12.644.276.954.300.049 D12.776.467.942.200.900 D12.776.467.942.300.049 D23.529.942.200.900 D23.529.942.300.049
|
| Concept/Terms |
Bone Morphogenetic Protein 15- Bone Morphogenetic Protein 15
- Growth Differentiation Factor 9B
- GDF-9-Related Protein
- GDF 9 Related Protein
- GDF-9B
- BMP-15
- GDF-9 Related Factor
- GDF 9 Related Factor
|
Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein 15".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein 15".
This graph shows the total number of publications written about "Bone Morphogenetic Protein 15" by people in this website by year, and whether "Bone Morphogenetic Protein 15" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bone Morphogenetic Protein 15" by people in Profiles.
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In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells. Nat Commun. 2017 06 12; 8:15680.
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Calreticulin is required for development of the cumulus oocyte complex and female fertility. Sci Rep. 2015 Sep 21; 5:14254.
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Effects of 11-ketotestosterone and temperature on inhibin subunit mRNA levels in the ovary of the shortfinned eel, Anguilla australis. Comp Biochem Physiol B Biochem Mol Biol. 2015 Sep; 187:14-21.
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Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities. Biol Reprod. 2014 Dec; 91(6):142.
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Evolutionary origin of bone morphogenetic protein 15 and growth and differentiation factor 9 and differential selective pressure between mono- and polyovulating species. Biol Reprod. 2014 Oct; 91(4):83.
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Reply to Mottershead et al.: GDF9:BMP15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):E2258.
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Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8):E776-85.
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Estrogen promotes the development of mouse cumulus cells in coordination with oocyte-derived GDF9 and BMP15. Mol Endocrinol. 2010 Dec; 24(12):2303-14.
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Mouse oocytes enable LH-induced maturation of the cumulus-oocyte complex via promoting EGF receptor-dependent signaling. Mol Endocrinol. 2010 Jun; 24(6):1230-9.
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Stable expression and characterization of N-terminal tagged recombinant human bone morphogenetic protein 15. Mol Hum Reprod. 2009 Dec; 15(12):779-88.