Bone Morphogenetic Protein 5
"Bone Morphogenetic Protein 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator of the growth of CHONDROCYTES and the synthesis of cartilage matrix proteins. Evidence for its role in cartilage formation can be seen in MICE, where genetic mutations that cause loss of bone morphogenetic protein 5 function result in the formation of small malformed ears.
| Descriptor ID |
D055417
|
| MeSH Number(s) |
D12.644.276.954.200.500 D12.776.467.942.200.500 D23.529.942.200.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein 5".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein 5".
This graph shows the total number of publications written about "Bone Morphogenetic Protein 5" by people in this website by year, and whether "Bone Morphogenetic Protein 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bone Morphogenetic Protein 5" by people in Profiles.
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A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-? Superfamily. Cell Syst. 2018 10 24; 7(4):422-437.e7.
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Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma. Cancer Res. 2013 Jul 15; 73(14):4559-70.
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Deletion of Smad4 in fibroblasts leads to defective chondrocyte maturation and cartilage production in a TGF? type II receptor independent manner. Biochem Biophys Res Commun. 2011 Apr 22; 407(4):633-9.