"Oncostatin M" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
| Descriptor ID |
D053683
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| MeSH Number(s) |
D12.644.276.374.562 D12.776.467.374.562 D23.529.374.562
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oncostatin M".
Below are MeSH descriptors whose meaning is more specific than "Oncostatin M".
This graph shows the total number of publications written about "Oncostatin M" by people in this website by year, and whether "Oncostatin M" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Oncostatin M" by people in Profiles.
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Oncostatin-M Does Not Predict Treatment Response in Inflammatory Bowel Disease in a Pediatric Cohort. J Pediatr Gastroenterol Nutr. 2021 09 01; 73(3):352-357.
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Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. Cancer Res. 2021 10 15; 81(20):5336-5352.
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Integrative transcriptomic analysis for linking acute stress responses to squamous cell carcinoma development. Sci Rep. 2020 10 14; 10(1):17209.
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miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer. Cell Rep. 2019 12 24; 29(13):4389-4406.e10.
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Adrenergic receptor agonists induce the differentiation of pluripotent stem cell-derived hepatoblasts into hepatocyte-like cells. Sci Rep. 2017 12 01; 7(1):16734.
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JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non-Small Cell Lung Cancer. Mol Cancer Ther. 2017 10; 16(10):2234-2245.
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Integrated MicroRNA-mRNA Profiling Identifies Oncostatin M as a Marker of Mesenchymal-Like ER-Negative/HER2-Negative Breast Cancer. Int J Mol Sci. 2017 Jan 19; 18(1).
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The reparative function of cardiomyocytes in the infarcted myocardium. Cell Metab. 2015 Jun 02; 21(6):797-8.
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Endothelium-derived GM-CSF influences expression of oncostatin M. Am J Physiol Cell Physiol. 2011 Oct; 301(4):C947-53.
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Early differential expression of oncostatin M in obstructive nephropathy. J Interferon Cytokine Res. 2010 Jul; 30(7):513-23.