"Versicans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
HYALURONAN-containing proteoglycans found in the EXTRACELLULAR MATRIX of a variety of tissues and organs. Several versican isoforms exist due to multiple ALTERNATIVE SPLICING of the versican MESSENGER RNA.
| Descriptor ID |
D053675
|
| MeSH Number(s) |
D09.698.735.200.750 D12.776.395.650.750.687.800 D12.776.503.280.437.800 D12.776.860.300.885
|
| Concept/Terms |
Versicans- Versicans
- Versican
- Chondroitin Sulfate Proteoglycan Core Protein 2
|
Below are MeSH descriptors whose meaning is more general than "Versicans".
Below are MeSH descriptors whose meaning is more specific than "Versicans".
This graph shows the total number of publications written about "Versicans" by people in this website by year, and whether "Versicans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2008 | 0 | 3 | 3 |
| 2010 | 1 | 2 | 3 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Versicans" by people in Profiles.
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Versican provides the provisional matrix for uterine spiral artery dilation and fetal growth. Matrix Biol. 2023 01; 115:16-31.
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TIGIT is the central player in T-cell suppression associated with CAR T-cell relapse in mantle cell lymphoma. Mol Cancer. 2022 09 26; 21(1):185.
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Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease. Nat Cardiovasc Res. 2022 01; 1(1):28-44.
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Inhibitors of metalloprotease, ?-sectretase, protein kinase C and Rho kinase inhibit wild-type adenoviral replication. PLoS One. 2020; 15(7):e0236175.
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Versican is differentially regulated in the adventitial and medial layers of human vein grafts. PLoS One. 2018; 13(9):e0204045.
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Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice. Sci Rep. 2017 09 27; 7(1):12351.
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Versican G1 domain enhances adenoviral-mediated transgene expression and can be modulated by inhibitors of the Janus kinase (JAK)/STAT and Src family kinase pathways. J Biol Chem. 2017 09 01; 292(35):14381-14390.
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TGF-? modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment. Cancer Res. 2013 Aug 15; 73(16):5016-28.
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Proteomics portrait of archival lesions of chronic pancreatitis. PLoS One. 2011; 6(11):e27574.
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Differential proteoglycan and hyaluronan distribution in calcified aortic valves. Cardiovasc Pathol. 2011 Nov-Dec; 20(6):334-42.