"Pyruvate Carboxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.
| Descriptor ID |
D011766
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| MeSH Number(s) |
D08.811.464.257.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyruvate Carboxylase".
Below are MeSH descriptors whose meaning is more specific than "Pyruvate Carboxylase".
This graph shows the total number of publications written about "Pyruvate Carboxylase" by people in this website by year, and whether "Pyruvate Carboxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyruvate Carboxylase" by people in Profiles.
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Multidrug resistance P-glycoprotein monoclonal antibody JSB-1 crossreacts with pyruvate carboxylase. J Histochem Cytochem. 1995 Dec; 43(12):1187-92.
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MDR1 gene-specific monoclonal antibody C494 cross-reacts with pyruvate carboxylase. Cancer Res. 1994 Mar 15; 54(6):1536-41.