Tartrate-Resistant Acid Phosphatase
"Tartrate-Resistant Acid Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
| Descriptor ID |
D000071681
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| MeSH Number(s) |
D08.811.277.352.650.025.500 D08.811.277.352.650.625.862
|
| Concept/Terms |
Tartrate-Resistant Acid Phosphatase- Tartrate-Resistant Acid Phosphatase
- Acid Phosphatase, Tartrate-Resistant
- Phosphatase, Tartrate-Resistant Acid
- Tartrate Resistant Acid Phosphatase
- TRAcP
TRAP Type 5 AcPase- TRAP Type 5 AcPase
- Acid Phosphatase V
- Phosphatase V, Acid
- V, Acid Phosphatase
- AcPase V
- V, AcPase
- Type 5 Acid Phosphatase
- Tartrate-Resistant Acid Phosphatase Type 5
- Tartrate Resistant Acid Phosphatase Type 5
|
Below are MeSH descriptors whose meaning is more general than "Tartrate-Resistant Acid Phosphatase".
Below are MeSH descriptors whose meaning is more specific than "Tartrate-Resistant Acid Phosphatase".
This graph shows the total number of publications written about "Tartrate-Resistant Acid Phosphatase" by people in this website by year, and whether "Tartrate-Resistant Acid Phosphatase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tartrate-Resistant Acid Phosphatase" by people in Profiles.
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Myelofibrosis osteoclasts are clonal and functionally impaired. Blood. 2019 05 23; 133(21):2320-2324.
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Artemisinin inhibits breast cancer-induced osteolysis by inhibiting osteoclast formation and breast cancer cell proliferation. J Cell Physiol. 2019 08; 234(8):12663-12675.
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Exercise improves femoral whole-bone and tissue-level biomechanical properties in hyperphagic OLETF rats. Appl Physiol Nutr Metab. 2017 Aug; 42(8):884-892.
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Spondyloenchondrodysplasia Due to Mutations in ACP5: A Comprehensive Survey. J Clin Immunol. 2016 Apr; 36(3):220-34.
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Adult Brtl/+ mouse model of osteogenesis imperfecta demonstrates anabolic response to sclerostin antibody treatment with increased bone mass and strength. Osteoporos Int. 2014 Aug; 25(8):2097-107.
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Proinvasion metastasis drivers in early-stage melanoma are oncogenes. Cancer Cell. 2011 Jul 12; 20(1):92-103.
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Cathepsin K-sensitive poly(ethylene glycol) hydrogels for degradation in response to bone resorption. J Biomed Mater Res A. 2011 Jul; 98(1):53-62.
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Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro. J Thromb Thrombolysis. 2010 Oct; 30(3):251-62.
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Mecp2 deficiency decreases bone formation and reduces bone volume in a rodent model of Rett syndrome. Bone. 2009 Aug; 45(2):346-56.
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Transgenic mice that express Cre recombinase in osteoclasts. Genesis. 2004 Jul; 39(3):178-85.