COUP Transcription Factor II
"COUP Transcription Factor II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A COUP transcription factor that negatively regulates GENETIC TRANSCRIPTION and competes with other hormone receptors for the common response element AGGTCA. It can also stimulate transcription of genes involved in the metabolism of GLUCOSE and CHOLESTEROL.
| Descriptor ID |
D051837
|
| MeSH Number(s) |
D12.776.260.643.039.500 D12.776.260.703.200 D12.776.826.209.039.500 D12.776.930.780.750
|
| Concept/Terms |
COUP Transcription Factor II- COUP Transcription Factor II
- Apolipoprotein AI Regulatory Protein 1
- Chicken Ovalbumin Upstream Promoter-Transcription Factor II
- Chicken Ovalbumin Upstream Promoter Transcription Factor II
- Nuclear Receptor Subfamily 2, Group F, Member 2
- COUP-TF2 Protein
- COUP TF2 Protein
- COUP-TFII Protein
- COUP TFII Protein
- Nuclear Receptor NR2F2
- ApoAI Regulatory Protein-1
- ApoAI Regulatory Protein 1
- COUP Transcription Factor 2
|
Below are MeSH descriptors whose meaning is more general than "COUP Transcription Factor II".
Below are MeSH descriptors whose meaning is more specific than "COUP Transcription Factor II".
This graph shows the total number of publications written about "COUP Transcription Factor II" by people in this website by year, and whether "COUP Transcription Factor II" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 3 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 2 | 4 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 5 | 3 | 8 |
| 2011 | 2 | 0 | 2 |
| 2012 | 6 | 0 | 6 |
| 2013 | 3 | 0 | 3 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 3 | 1 | 4 |
| 2017 | 3 | 0 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "COUP Transcription Factor II" by people in Profiles.
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Targeted deletion of NR2F2 and VCAM1 in theca cells impacts ovarian follicular development: insights into polycystic ovary syndrome??. Biol Reprod. 2024 Apr 11; 110(4):782-797.
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The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancy. Front Endocrinol (Lausanne). 2023; 14:1229033.
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Heterozygous rare variants in NR2F2 cause a recognizable multiple congenital anomaly syndrome with developmental delays. Eur J Hum Genet. 2023 10; 31(10):1117-1124.
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YAP1 overexpression contributes to the development of enzalutamide resistance by induction of cancer stemness and lipid metabolism in prostate cancer. Oncogene. 2021 04; 40(13):2407-2421.
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Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. PLoS Genet. 2020 06; 16(6):e1008868.
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Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment. Sci Adv. 2020 05; 6(18):eaaz8031.
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Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019 10; 5(10):eaax6366.
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Molecular regulation of arteriovenous endothelial cell specification. F1000Res. 2019; 8.
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VCAM1 Is Induced in Ovarian Theca and Stromal Cells in a Mouse Model of Androgen Excess. Endocrinology. 2019 06 01; 160(6):1377-1393.
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Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice. Science. 2017 08 18; 357(6352):717-720.