"Lac Repressors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bacterial repressor proteins that bind to the LAC OPERON and thereby prevent the synthesis of proteins involved in catabolism of LACTOSE. When lactose levels are high lac repressors undergo an allosteric change that causes their release from the DNA and the resumption of lac operon transcription.
| Descriptor ID |
D056968
|
| MeSH Number(s) |
D12.776.097.521 D12.776.260.703.600 D12.776.930.780.781
|
| Concept/Terms |
Lac Repressors- Lac Repressors
- Repressors, Lac
- LacI Proteins
- Proteins, LacI
- Lac Repressor
- Repressor, Lac
|
Below are MeSH descriptors whose meaning is more general than "Lac Repressors".
Below are MeSH descriptors whose meaning is more specific than "Lac Repressors".
This graph shows the total number of publications written about "Lac Repressors" by people in this website by year, and whether "Lac Repressors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lac Repressors" by people in Profiles.
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Mapping Protein-Protein Interaction Interface Peptides with Jun-Fos Assisted Phage Display and Deep Sequencing. ACS Synth Biol. 2020 07 17; 9(7):1882-1896.
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The lac repressor hinge helix in context: The effect of the DNA binding domain and symmetry. Biochim Biophys Acta Gen Subj. 2020 04; 1864(4):129538.
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Price of disorder in the lac repressor hinge helix. Biopolymers. 2019 Jan; 110(1):e23239.
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DksA involvement in transcription fidelity buffers stochastic epigenetic change. Nucleic Acids Res. 2015 Dec 02; 43(21):10190-9.
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Removal of 8-oxo-GTP by MutT hydrolase is not a major contributor to transcriptional fidelity. Nucleic Acids Res. 2014 Oct 29; 42(19):12015-26.
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Heritable change caused by transient transcription errors. PLoS Genet. 2013 Jun; 9(6):e1003595.
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Adaptive evolution of the lactose utilization network in experimentally evolved populations of Escherichia coli. PLoS Genet. 2012 Jan; 8(1):e1002444.
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Multicopy plasmids affect replisome positioning in Bacillus subtilis. J Bacteriol. 2004 Nov; 186(21):7084-90.
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Perturbation from a distance: mutations that alter LacI function through long-range effects. Biochemistry. 2003 Dec 02; 42(47):14004-16.
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A regulatory system for target gene expression. Front Biosci. 1998 Jan 01; 3:c1-7.