Zinc Finger E-box Binding Homeobox 2
"Zinc Finger E-box Binding Homeobox 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME.
| Descriptor ID |
D000074165
|
| MeSH Number(s) |
D12.776.260.400.883 D12.776.260.703.700 D12.776.930.780.918
|
| Concept/Terms |
Zinc Finger E-box Binding Homeobox 2- Zinc Finger E-box Binding Homeobox 2
- Zinc Finger E box Binding Homeobox 2
- Zinc Finger E-box Binding Homeobox 2 Protein
- Zinc Finger E box Binding Homeobox 2 Protein
- Zeb2 Transcription Factor
- Transcription Factor, Zeb2
- Smad-Interacting Protein 1
- Smad Interacting Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Zinc Finger E-box Binding Homeobox 2".
Below are MeSH descriptors whose meaning is more specific than "Zinc Finger E-box Binding Homeobox 2".
This graph shows the total number of publications written about "Zinc Finger E-box Binding Homeobox 2" by people in this website by year, and whether "Zinc Finger E-box Binding Homeobox 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 4 | 4 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Zinc Finger E-box Binding Homeobox 2" by people in Profiles.
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Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc. Signal Transduct Target Ther. 2021 06 25; 6(1):240.
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Functional Hierarchy and Cooperation of EMT Master Transcription Factors in Breast Cancer Metastasis. Mol Cancer Res. 2021 05; 19(5):784-798.
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Cerebral ischemia induces TRPC6 via HIF1a/ZEB2 axis in the glomerular podocytes and contributes to proteinuria. Sci Rep. 2019 11 29; 9(1):17897.
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DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer. Proc Natl Acad Sci U S A. 2018 12 18; 115(51):E11978-E11987.
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Hypoxia induces ZEB2 in podocytes: Implications in the pathogenesis of proteinuria. J Cell Physiol. 2019 05; 234(5):6503-6518.
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Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression. Theranostics. 2017; 7(19):4836-4849.
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Progesterone Receptor Signaling in Uterine Myometrial Physiology and Preterm Birth. Curr Top Dev Biol. 2017; 125:171-190.
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Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Genome Res. 2017 07; 27(7):1112-1125.
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miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance. J Mol Med (Berl). 2016 06; 94(6):629-44.
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Clonal evolution of acute myeloid leukemia relapsed after 19 years of remission. Am J Hematol. 2015 Jul; 90(7):E134-5.