"Coagulase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
| Descriptor ID |
D003030
|
| MeSH Number(s) |
D08.811.277.656.300.174 D12.776.097.181
|
| Concept/Terms |
Staphylococcal Clumping Factor- Staphylococcal Clumping Factor
- Clumping Factor, Staphylococcal
- Factor, Staphylococcal Clumping
- Clumping Factor (Staphylococcal)
|
Below are MeSH descriptors whose meaning is more general than "Coagulase".
Below are MeSH descriptors whose meaning is more specific than "Coagulase".
This graph shows the total number of publications written about "Coagulase" by people in this website by year, and whether "Coagulase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "Coagulase" by people in Profiles.
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Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial. JAMA. 2018 09 25; 320(12):1249-1258.
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Impact of Serum Vancomycin Trough Levels in the Treatment of Central Nervous System Shunt Infections Caused by Coagulase-Negative Staphylococci. Pediatr Neurosurg. 2018; 53(4):243-246.
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Morbidity and mortality of coagulase-negative staphylococcal sepsis in very-low-birth-weight infants. World J Pediatr. 2018 06; 14(3):269-273.
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Distinguishing true coagulase-negative Staphylococcus infections from contaminants in the neonatal intensive care unit. J Perinatol. 2013 Jan; 33(1):52-8.
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Emergence of linezolid-resistant coagulase-negative Staphylococcus in a cancer centre linked to increased linezolid utilization. J Antimicrob Chemother. 2010 Sep; 65(9):2001-4.
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Management of the catheter in documented catheter-related coagulase-negative staphylococcal bacteremia: remove or retain? Clin Infect Dis. 2009 Oct 15; 49(8):1187-94.
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Differentiating culture samples representing coagulase-negative staphylococcal bacteremia from those representing contamination by use of time-to-positivity and quantitative blood culture methods. J Clin Microbiol. 2009 Oct; 47(10):3255-60.
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Interrupted time series analysis of vancomycin compared to cefuroxime for surgical prophylaxis in patients undergoing cardiac surgery. Antimicrob Agents Chemother. 2008 Feb; 52(2):446-51.
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Coagulase-negative staphylococcal infections in the neonate and child: an update. Semin Pediatr Infect Dis. 2006 Jul; 17(3):120-7.
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Features of invasive staphylococcal disease in neonates. Pediatrics. 2004 Oct; 114(4):953-61.