Protein-Arginine N-Methyltransferases
"Protein-Arginine N-Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the methylation of arginine residues of proteins to yield N-mono- and N,N-dimethylarginine. This enzyme is found in many organs, primarily brain and spleen.
| Descriptor ID |
D011484
|
| MeSH Number(s) |
D08.811.913.555.500.800.750
|
| Concept/Terms |
Protein-Arginine N-Methyltransferases- Protein-Arginine N-Methyltransferases
- N-Methyltransferases, Protein-Arginine
- Protein Arginine N Methyltransferases
- Protein Arginine Methyltransferase
- Arginine Methyltransferase, Protein
- Methyltransferase, Protein Arginine
- Protein Methyltransferase I
- Protein-Arginine N-Methyltransferase
- N-Methyltransferase, Protein-Arginine
- Protein Arginine N Methyltransferase
- Arginine Methylase
- Protein Methylase I
|
Below are MeSH descriptors whose meaning is more general than "Protein-Arginine N-Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Protein-Arginine N-Methyltransferases".
This graph shows the total number of publications written about "Protein-Arginine N-Methyltransferases" by people in this website by year, and whether "Protein-Arginine N-Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 2 | 3 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Protein-Arginine N-Methyltransferases" by people in Profiles.
-
Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity. Nat Cancer. 2024 04; 5(4):601-624.
-
FACS-based genome-wide CRISPR screens define key regulators of DNA damage signaling pathways. Mol Cell. 2023 08 03; 83(15):2810-2828.e6.
-
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase. ACS Chem Biol. 2023 04 21; 18(4):734-745.
-
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI. Brain. 2023 02 13; 146(2):492-506.
-
Biallelic PRMT7 pathogenic variants are associated with a recognizable syndromic neurodevelopmental disorder with short stature, obesity, and craniofacial and digital abnormalities. Genet Med. 2023 01; 25(1):135-142.
-
TFEB, SIRT1, CARM1, Beclin-1 expression and PITX2 methylation in breast cancer chemoresistance: a retrospective study. BMC Cancer. 2021 Oct 18; 21(1):1118.
-
Rational Design and Synthesis of Selective PRMT4 Inhibitors: A New Chemotype for Development of Cancer Therapeutics*. ChemMedChem. 2021 04 08; 16(7):1116-1125.
-
Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators. J Immunother Cancer. 2021 02; 9(2).
-
Methylation of HSP70 Orchestrates Its Binding to and Stabilization of BCL2 mRNA and Renders Pancreatic Cancer Cells Resistant to Therapeutics. Cancer Res. 2020 10 15; 80(20):4500-4513.
-
CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas. Leukemia. 2020 12; 34(12):3269-3285.