Protein-Arginine N-Methyltransferases
"Protein-Arginine N-Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the methylation of arginine residues of proteins to yield N-mono- and N,N-dimethylarginine. This enzyme is found in many organs, primarily brain and spleen.
| Descriptor ID |
D011484
|
| MeSH Number(s) |
D08.811.913.555.500.800.750
|
| Concept/Terms |
Protein-Arginine N-Methyltransferases- Protein-Arginine N-Methyltransferases
- N-Methyltransferases, Protein-Arginine
- Protein Arginine N Methyltransferases
- Protein Arginine Methyltransferase
- Arginine Methyltransferase, Protein
- Methyltransferase, Protein Arginine
- Protein Methyltransferase I
- Protein-Arginine N-Methyltransferase
- N-Methyltransferase, Protein-Arginine
- Protein Arginine N Methyltransferase
- Arginine Methylase
- Protein Methylase I
|
Below are MeSH descriptors whose meaning is more general than "Protein-Arginine N-Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Protein-Arginine N-Methyltransferases".
This graph shows the total number of publications written about "Protein-Arginine N-Methyltransferases" by people in this website by year, and whether "Protein-Arginine N-Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 4 | 2 | 6 |
| 2005 | 7 | 1 | 8 |
| 2006 | 3 | 1 | 4 |
| 2007 | 4 | 2 | 6 |
| 2008 | 2 | 0 | 2 |
| 2009 | 7 | 1 | 8 |
| 2010 | 2 | 5 | 7 |
| 2011 | 2 | 3 | 5 |
| 2012 | 5 | 1 | 6 |
| 2013 | 4 | 0 | 4 |
| 2014 | 1 | 2 | 3 |
| 2015 | 5 | 1 | 6 |
| 2016 | 4 | 1 | 5 |
| 2017 | 4 | 1 | 5 |
| 2018 | 4 | 0 | 4 |
| 2019 | 3 | 0 | 3 |
| 2020 | 5 | 1 | 6 |
| 2021 | 7 | 3 | 10 |
| 2022 | 3 | 2 | 5 |
| 2023 | 2 | 8 | 10 |
To return to the timeline,
click here.
Below are the most recent publications written about "Protein-Arginine N-Methyltransferases" by people in Profiles.
-
PRT543, a protein arginine methyltransferase 5 inhibitor, in patients with advanced adenoid cystic carcinoma: An open-label, phase I dose-expansion study. Oral Oncol. 2024 Feb; 149:106634.
-
PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition. Cell Rep Med. 2023 12 19; 4(12):101326.
-
HPV-positive clinically advanced squamous cell carcinoma of the urinary bladder (aBSCC): A comprehensive genomic profiling (CGP) study. Urol Oncol. 2023 12; 41(12):486.e15-486.e23.
-
CARM1 arginine methyltransferase as a therapeutic target for cancer. J Biol Chem. 2023 09; 299(9):105124.
-
Effectors and effects of arginine methylation. Biochem Soc Trans. 2023 04 26; 51(2):725-734.
-
The cancer testis antigen TDRD1 regulates prostate cancer proliferation by associating with the snRNP biogenesis machinery. Oncogene. 2023 06; 42(22):1821-1831.
-
CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth. Cell Rep. 2023 04 25; 42(4):112316.
-
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase. ACS Chem Biol. 2023 04 21; 18(4):734-745.
-
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI. Brain. 2023 02 13; 146(2):492-506.
-
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nat Commun. 2023 01 23; 14(1):363.