Transcription Factors, General
"Transcription Factors, General" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription. Although their binding may be localized to distinct sequence and structural motifs within the DNA they are considered non-specific with regard to the specific gene being transcribed.
| Descriptor ID |
D035165
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| MeSH Number(s) |
D12.776.260.775 D12.776.930.930
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factors, General".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factors, General".
This graph shows the total number of publications written about "Transcription Factors, General" by people in this website by year, and whether "Transcription Factors, General" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factors, General" by people in Profiles.
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Neurodevelopmental and other phenotypes recurrently associated with heterozygous BAZ2B loss-of-function variants. Am J Med Genet A. 2024 03; 194(3):e63445.
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BAZ2B haploinsufficiency as a cause of developmental delay, intellectual disability, and autism spectrum disorder. Hum Mutat. 2020 05; 41(5):921-925.
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A four-gene transcript score to predict metastatic-lethal progression in men treated for localized prostate cancer: Development and validation studies. Prostate. 2019 10; 79(14):1589-1596.
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Cell biology. RNA metabolism and oncogenesis. Science. 2008 Apr 25; 320(5875):461-2.
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Elongation factor SII contacts the 3'-end of RNA in the RNA polymerase II elongation complex. J Biol Chem. 1996 Sep 13; 271(37):22301-4.