G-Protein-Coupled Receptor Kinases
"G-Protein-Coupled Receptor Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine-threonine kinases that are specific for G-PROTEIN-COUPLED RECEPTORS. They are regulatory proteins that play a role in G-protein-coupled receptor densensitization.
| Descriptor ID |
D054768
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| MeSH Number(s) |
D08.811.913.696.620.682.700.364 D12.644.360.293 D12.776.476.293
|
| Concept/Terms |
G-Protein-Coupled Receptor Kinases- G-Protein-Coupled Receptor Kinases
- G Protein Coupled Receptor Kinases
- Kinases, G-Protein-Coupled Receptor
- Receptor Kinases, G-Protein-Coupled
|
Below are MeSH descriptors whose meaning is more general than "G-Protein-Coupled Receptor Kinases".
Below are MeSH descriptors whose meaning is more specific than "G-Protein-Coupled Receptor Kinases".
This graph shows the total number of publications written about "G-Protein-Coupled Receptor Kinases" by people in this website by year, and whether "G-Protein-Coupled Receptor Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "G-Protein-Coupled Receptor Kinases" by people in Profiles.
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Clinical utility of lymphocyte to C-reactive protein ratio in predicting survival and postoperative complication for esophago-gastric junction cancer. Surg Oncol. 2022 Sep; 44:101842.
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G protein-coupled receptor kinase 6 acts as a critical regulator of cytokine-induced hyperalgesia by promoting phosphatidylinositol 3-kinase and inhibiting p38 signaling. Mol Med. 2012 May 09; 18:556-64.
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Potential dopamine-1 receptor stimulation in hypertension management. Curr Hypertens Rep. 2011 Aug; 13(4):294-302.
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Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation. Mol Pharmacol. 2010 Mar; 77(3):405-15.
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G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia. Brain Behav Immun. 2009 Jan; 23(1):18-26.
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G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice. Gut. 2007 Jun; 56(6):847-54.
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beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J Biol Chem. 2006 Jan 13; 281(2):1261-73.
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GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo. J Leukoc Biol. 2004 Apr; 75(4):698-704.
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Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6. J Immunol. 2003 Dec 01; 171(11):6128-34.
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Changes in the G-protein-coupled receptor desensitization machinery during relapsing-progressive experimental allergic encephalomyelitis. J Neuroimmunol. 2003 Apr; 137(1-2):79-86.