"I-kappa B Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit.
| Descriptor ID |
D051550
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.494 D12.644.360.361 D12.776.476.378
|
| Concept/Terms |
I-kappa B Kinase- I-kappa B Kinase
- B Kinase, I-kappa
- Kinase, I-kappa B
- NK-kappa B-Activating Kinase NAK
- NK kappa B Activating Kinase NAK
- IkappaB Kinase
- Kinase, IkappaB
- I kappa B Kinase
IkappaB Kinase gamma- IkappaB Kinase gamma
- IKK gamma
- NF-kappaB Essential Modifier
- Essential Modifier, NF-kappaB
- NF kappaB Essential Modifier
IkappaB Kinase alpha- IkappaB Kinase alpha
- Kinase alpha, IkappaB
- IKK 1 Kinase
- IKK alpha
- Conserved Helix-Loop-Helix Ubiquitous Kinase
- Conserved Helix Loop Helix Ubiquitous Kinase
- CHUK Kinase
- I Kappa B alpha-Associated Protein Kinase
- I Kappa B alpha Associated Protein Kinase
- IkappaBalpha Kinase
|
Below are MeSH descriptors whose meaning is more general than "I-kappa B Kinase".
Below are MeSH descriptors whose meaning is more specific than "I-kappa B Kinase".
This graph shows the total number of publications written about "I-kappa B Kinase" by people in this website by year, and whether "I-kappa B Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 4 | 4 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 12 | 12 |
| 2001 | 0 | 9 | 9 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 13 | 13 |
| 2005 | 4 | 6 | 10 |
| 2006 | 6 | 7 | 13 |
| 2007 | 10 | 7 | 17 |
| 2008 | 7 | 4 | 11 |
| 2009 | 7 | 4 | 11 |
| 2010 | 5 | 3 | 8 |
| 2011 | 3 | 7 | 10 |
| 2012 | 9 | 7 | 16 |
| 2013 | 4 | 0 | 4 |
| 2014 | 3 | 1 | 4 |
| 2015 | 0 | 2 | 2 |
| 2016 | 2 | 3 | 5 |
| 2017 | 3 | 2 | 5 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "I-kappa B Kinase" by people in Profiles.
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Brazilin-Ce nanoparticles attenuate inflammation by de/anti-phosphorylation of IKK?. Biomaterials. 2024 Mar; 305:122466.
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Got PIDD1? Natural killer cells clear polyploid cells to ensure a balanced genome. EMBO J. 2023 10 16; 42(20):e115307.
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Plasma Metagenomic Sequencing Expedites Diagnosis of Disseminated BCG in an Infant With IKBKB Mutation. Pediatr Infect Dis J. 2022 05 01; 41(5):430-435.
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ROR activation by Nobiletin enhances antitumor efficacy via suppression of I?B/NF-?B signaling in triple-negative breast cancer. Cell Death Dis. 2022 04 19; 13(4):374.
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Transient blockade of TBK1/IKKe allows efficient transduction of primary human natural killer cells with vesicular stomatitis virus G-pseudotyped lentiviral vectors. Cytotherapy. 2021 09; 23(9):787-792.
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PRSS50 is a testis protease responsible for proper sperm tail formation and function. Development. 2021 04 15; 148(8).
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Inhibition of TBK1/IKKe Promotes Regeneration of Pancreatic ?-cells. Sci Rep. 2018 10 22; 8(1):15587.
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GLK-IKK? signaling induces dimerization and translocation of the AhR-ROR?t complex in IL-17A induction and autoimmune disease. Sci Adv. 2018 09; 4(9):eaat5401.
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IDH2 Deficiency Aggravates Fructose-Induced NAFLD by Modulating Hepatic Fatty Acid Metabolism and Activating Inflammatory Signaling in Female Mice. Nutrients. 2018 May 27; 10(6).
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Coactivation of Estrogen Receptor and IKK? Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer. Cancer Res. 2018 02 15; 78(4):974-984.